A Cholinergic - Regulated Circuit Coordinates the Maintenance and Bi-Stable States of a Sensory - Motor Behavior during Caenorhabditis
elegans Male Copulation
Developmental alterations of the C.
elegans male anal depressor morphology and function require sex - specific cell autonomous and cell non-autonomous interactions.
Not exact matches
C.
elegans comes in two sexes:
males and hermaphrodites.
To reproduce, C.
elegans must produce gametes, that is
male sperm and female eggs.
In the nematode Caenorhabditis
elegans, the presence of
males accelerated aging and shortened the life span of individuals of the opposite sex (hermaphrodites), including long - lived or sterile hermaphrodites.
However the only Boule homologs functionally characterized exhibit divergent roles in reproduction, with Drosophila boule necessary for
male reproduction and the C.
elegans boule homolog, daz - 1, required for egg production [39], [40].
Despite a large number of sex - specific gametogenesis proteins uncovered in the model organisms Drosophila, C.
elegans and mice, no conserved
male - or female - specific gametogenic factors common to all lineages of animals have been clearly demonstrated [30]--[33].
Given that mouse Boule is required for sperm production like fly boule but different from C.
elegans daz - 1, we propose that Urbilaterian Boule had an ancestral function in
male gametogenesis which was lost during the evolution of the nematode lineage (Figure 7).
Loss - of - function phenotypes of Boule homologs in Drosophila and Caenorhabditis
elegans reveal their divergent roles in reproduction, with boule required for
male reproduction in flies and for oogenesis in the worm [39], [40].