Sentences with phrase «elegans aging research»
Our work will not only address fundamental questions about the mechanisms of aging, but also provide a platform to greatly accelerate C. elegans aging research.
http://www.ellisonfoundation.org/ Not exact matches
When Gordon Lithgow at the Buck Institute for Research on Aging in Novato, California, and colleagues grew the soil - dwelling nematode Caenorhabditis elegans in agar plates soaked in thioflavin T — a dye used to visualise clusters of amyloid beta protein — they found that the worms lived 30 to 70 per cent longer than average.
Tatar's research, along with simultaneous independent work by Linda Partridge of University College London, U.K., and her colleagues, demonstrated that an insulin - like signaling pathway controls diapause and aging in flies — similar to what had already been found in the roundworm Caenorhabiditis elegans (see «Growing Old Together»).
To study how splicing might affect aging, the researchers looked to Caenorhabditis elegans, a species of roundworm that's often used as a precursor to human tests in biological research, thanks to it having a genome very similar to ours.
This year the organizers overtly recognized the history of our biomedical research niche in which C. elegans nematodes are used as a model organism (see our SAGE blog on how C. elegans models are used to study aging).
In particular, research with the roundworm C. elegans, aided by its short lifespan and easily manipulated genetics, has identified a number of pathways that regulate aging, such as insulin / insulin - like signaling, dietary restriction, heat shock resistance, and reproductive and sensory signaling pathways.
Rogers studies the molecular mechanisms underlying aging in C. elegans, a tiny, soil - dwelling roundworm that is a favorite animal model in aging research because its short lifespan allows scientists to quickly assess the effect of anti-aging interventions and because it shares many of its genes with humans.