Our studies suggest that direct activation of membrane chloride conductances is a general mechanism of action for biogenic amines in the modulation of C.
elegans behavior.
Key aspects of ischemia - reperfusion can be modeled by a Caenorhabditis
elegans behavior, the O2 - ON response, which is suppressed by hypoxic preconditioning or inactivation of the O2 - sensing HIF (hypoxia - inducible factor) hydroxylase EGL - 9.
Not exact matches
Additionally, C.
elegans continued to change its
behavior even after the fear - chemical was removed.
The sexual
behavior of the roundworm C.
elegans is unusual, to say the least.
As a result, alcohol - exposed worms stop wriggling — the C.
elegans version of the sluggish, uncoordinated
behavior characteristic of inebriated humans.
With further experimental analysis, the scientists identified two distinct genetic variants that resulted in these sensitivity differences, suggesting that in crowded places, wild C.
elegans populations with a specific genetic variation adopt different
behaviors than those who don't.
In the wild, C.
elegans worms in the quest for food alternate between an exploratory
behavior called roaming and a less active
behavior called dwelling, where the worms essentially «hunker down and eat,» Bargmann says.
To overcome this technical limitation, we will study the mating
behavior of a simple animal, the tiny roundworm C.
elegans.
We also observe this process during development in C.
elegans, and use measures of P granule growth rate, size distribution, and mechanical properties to test possible physical models that could underlie this
behavior.
Bargmann will split her presentation between her work at CZI and her own research at Rockefeller University in New York, where she studies C.
elegans to unravel the mysteries of nervous system signaling and
behavior.
C.
elegans is a lab - friendly model species for research on how chemical signals affect development and
behavior.
Professor Bargmann then embarked upon what was to become a lifetime mission to define how genes and the environment influence
behavior by dissecting the neural circuitry of C.
elegans and the genes, receptors, and signaling molecules involved in such
behavior as feeding and responses to odors.
Caenorhabditis
elegans, a worm with just 302 neurons, shows considerable sophistication in its
behaviors, and its defined neuronal wiring and genetic accessibility make it an ideal subject in which to study these interactions.
As a postdoctoral fellow in Dr. Cori Bargmann's lab at the Rockefeller University, she showed that the nematode C.
elegans produces a neuropeptide that is an evolutionary precursor of the mammalian peptides vasopressin and oxytocin, and mapped a neural circuit by which this molecule, nematocin, modulates mating
behavior.
Using C.
elegans as a model, Bargmann's laboratory characterizes genes and neural pathways that allow the nervous system to generate flexible
behaviors.
A Cholinergic - Regulated Circuit Coordinates the Maintenance and Bi-Stable States of a Sensory - Motor
Behavior during Caenorhabditis
elegans Male Copulation
Postsynaptic ERG potassium channels limit muscle excitability to allow distinct egg - laying
behavior states in Caenorhabditis
elegans.
C.
elegans Dopaminergic D2 - Like Receptors Delimit Recurrent Cholinergic - Mediated Motor Programs during a Goal - Oriented
Behavior
Professor Bargmann's pioneering work has provided important insights into the molecular switches and controls for C.
elegans movement and
behavior — many of which have human counterparts.
A team from the Salk Institute has discovered that a tiny worm — known as Caenorhabditis
elegans (C.
elegans)-- exhibits fear and anxiety
behaviors similarly to humans.