Adam Kupinski (Eckmann, MPG)-- «The Ste20 kinease GCK - 3 is essential for C.
elegans development and regulates centrosome maturation during meiosis» (2008)
Functional divergence of dafachronic acid pathways in the control of C.
elegans development and lifespan.
Not exact matches
«In this study, we used the small roundworm C.
elegans as a model to show that autophagy in the intestine is critical for lifespan extension,» said Malene Hansen, Ph.D., associate professor in SBP's
Development, Aging, and Regeneration Program and senior author of the study.
Strome noted that the findings in this study of transmission of histone methylation in C.
elegans have important implications in other organisms, even though different organisms use the repressive marker that was studied to regulate different genes during different aspects of
development.
True to his drifter roots, Ruvkun has, since then, gamely followed the road of science as it has twisted and turned toward his current pursuit: studying the neuroendocrine control of metabolism,
development, and longevity in C.
elegans.
In the late 1970s and 1980s, «worm talks» (as C.
elegans lectures were called) inevitably began with a description of
development in the normal worm and segued to whatever mutants the lecturer found intriguing.
When he failed, he devoted his attention to other genes involved in the
development of C.
elegans.
Now, scientists at the Technische Universität München (TUM) have characterized a small heat shock protein responsible for embryonic
development in the Caenorhabditis
elegans nematode.
To gain more insights into this highly specific degradation pattern, Qinghua Zhou et al. used electron microscopy and tomography to study sperm mitochondria (or paternal mitochondria) in Caenorhabditis
elegans, a type of roundworm, during early stages of
development.
«Scientists have learned a lot about
development, gene regulation, and cancer biology, among other things, by studying C.
elegans.
A study of the
development of the nervous system of the nematode Caenorhabditis
elegans by Neda Masoudi, Oliver Hobert and colleagues reveals a novel function for a member of the basic helix - loop - helix family of transcription factors in controlling terminal neuron differentiation (rather than initial commitment to a neural fate).
With only a single gene and a toolbox of forward and reverse genetic approaches at hand, C.
elegans offers an opportunity to explore the exact role of perlipin - related factors in fat regulation throughout
development of many different somatic and germline cells.
The Secretory Pathway Calcium ATPase PMR - 1 / SPCA1 Has Essential Roles in Cell Migration during Caenorhabditis
elegans Embryonic
Development.
Agata Rybarska (Eckmann, MPG)-- «he novel protein GLS - 1 modulates conserved mRNA regulatory machinery and has important roles in C.
elegans germline
development» (2010)
In a recent publication in the journal Genes &
Development titled «Neuronal inhibition of the autophagy nucleation complex extends lifespan in post-reproductive C.
elegans,» Dr. Holger Richly's lab at IMB has found some of the first genetic evidence that may put this question to rest.
Publication T. Wilhelm et al., Neuronal inhibition of the autophagy nucleation complex extends life span in post-reproductive C.
elegans, Genes &
Development, 7 September 2017, DOI: 10.1101 / gad.301648.117
C.
elegans, a 959 - celled Nobel magnet, helped explain cell suicide and launch genomics, and could now revolutionize drug
development.
We also observe this process during
development in C.
elegans, and use measures of P granule growth rate, size distribution, and mechanical properties to test possible physical models that could underlie this behavior.
Our lab uses a variety of model systems, such as the nematode C.
elegans, as well as in vitro culture systems, to address fundamental questions in cell cycle control during
development and tissue formation.
In the nematode worm, C.
elegans, cholinergic inputs to DD motor neurons are relocated to new positions during early larval
development.
Professor Horvitz had already made major contributions to understanding neural
development using C.
elegans as a simple model organism.
C.
elegans is a lab - friendly model species for research on how chemical signals affect
development and behavior.
When young C.
elegans larvae are cultured in adverse environmental conditions, they pause their
development by entering dauer quiescence — an arrested, non-aging and stress - resistant stage.
The microscopic Caenorhabditis
elegans worm may seem like an odd source of insight into human brain
development.
C.
elegans is an excellent model for understanding the genetic control of
development and physiology.