Sentences with phrase «elegans longevity»

Uncoupling lifespan and healthspan in Caenorhabditis elegans longevity mutants.

Not exact matches

Longevity researchers have long turned to C. elegans to learn more about the human aging process.

Scientists at the Buck Institute combined mutations in two pathways well - known for lifespan extension and report a synergistic five-fold extension of longevity in the nematode C. elegans.

True to his drifter roots, Ruvkun has, since then, gamely followed the road of science as it has twisted and turned toward his current pursuit: studying the neuroendocrine control of metabolism, development, and longevity in C. elegans.

In the nematode Caenorhabditis elegans, insulin / IGF signaling regulates adult longevity.

Reduced expression of the Caenorhabditis elegans p53 ortholog cep - 1 results in increased longevity.

Because C. elegans shares many of its genes with humans, scientists can apply what is learned from its study to extend human health and longevity.

In C. elegans, reductions in IIS increase stress resistance and longevity, effects that require the IIS inhibited FOXO protein DAF - 16.

Chen et al. (62) combined mutation in daf - 2 (similar allele to this study) with mutation in rsks - 1, C. elegans S6 kinase to reveal extreme longevity.

Since several longevity mutants (such as long - lived C. elegans or Drosophilia mutants19 20) manifest defects in a signaling mechanism that normally slows the rate of autophagic waste recycling, Dröge and other researchers have postulated that the aging - associated decline of mitochondrial autophagy or «mitophagy» may be the first most limiting mechanism that determines maximum life span in most animal species, including man.21 22

The longevity of Caenorhabditis elegans in soil.

The longevity effect of dietary restriction in Caenorhabditis elegans.