Sentences with phrase «elegans mutants»

C. elegans mutants that live twice as long as wild - type worms in laboratory conditions typically die sooner than wild - type worms in a natural soil.

Has laboratory protocols, photos and videos of C. elegans mutants, and a check - out system for C. elegans mutants and E. coli feeding strains.

Supporting resources include photos and video of C. elegans mutants, as well as a simple check - out system to obtain any of 80 C. elegans mutants and E. coli feeding strains.

While completing her postdoc, Murphy began to study C. elegans mutants that could live and reproduce twice as long as normal worms.

Not exact matches

To answer this question, Murphy tracked which genes were turned on and off over time in the oocytes and somatic cells in C. elegans IGF - 1 and TGF - β mutants, as well as wild - type worms.

Murphy found that the normal pattern of gene activation seen in aging wild - type C. elegans was reversed in the body cells and oocytes of IGF - 1 mutants.

«Combining mutants results in 5-fold lifespan extension in C. elegans.»

In the late 1970s and 1980s, «worm talks» (as C. elegans lectures were called) inevitably began with a description of development in the normal worm and segued to whatever mutants the lecturer found intriguing.

Finally Ruvkun's researchers came upon another grotesque mutant of C. elegans, known as let - 7, which literally bursts open in the final larval stage.

Uncoupling lifespan and healthspan in Caenorhabditis elegans longevity mutants.

One of the mutants carries a defect in Sch9, which resembles two genes in the C. elegans daf - 2 pathway.

In yeast and Caenorhabditis elegans, the majority of ORFs revealed by genomic sequencing have not been associated with mutant phenotypes, even in genomic regions that have been subjected to saturation mutagenesis (36 - 37).

Paralelly we will continue our work on C. elegans caveolins using dominant negative approach or producing deletion mutants.

Since several longevity mutants (such as long - lived C. elegans or Drosophilia mutants19 20) manifest defects in a signaling mechanism that normally slows the rate of autophagic waste recycling, Dröge and other researchers have postulated that the aging - associated decline of mitochondrial autophagy or «mitophagy» may be the first most limiting mechanism that determines maximum life span in most animal species, including man.21 22