Sentences with phrase «elegans worms»

For more information on these Nobel prize - winning studies see: (1) Aplysia sea slugs, (2) Caenorhabditis elegans worms, (3) Tetrahymena ciliates, (4) Drosophila melanogaster fruit flies, (5) Saccharomyces cerevisiae yeast

In the wild, C. elegans worms in the quest for food alternate between an exploratory behavior called roaming and a less active behavior called dwelling, where the worms essentially «hunker down and eat,» Bargmann says.

C. elegans worms feeding on bacterial food sources.

They tried out their approach on animals, using C. elegans worms and mice that had been genetically modified to develop the disease.

After bombarding hundreds of Caenorhabditis elegans worms with DNA - altering chemicals and screening the results, he found that the deletion of just one gene rendered the worms almost completely resistant to alcohol.

In matters of the fundamental molecular biology of aging, we mammals are not so different from tiny C. elegans worms.

For example, it might be possible to create C. elegans worms that protect fields of crops from disease by seeking out harmful bacteria.

Japanese researchers have discovered that Caenorhabditis elegans worms can detect cancer in people's urine.

Led by graduate student Patrick O'Hern, the team at Brown and the University of Cologne in Germany uncovered a complex cause - and - effect sequence in both C. elegans worm and mouse models of SMA.

In March's Discover Dialogue: The Caenorhabditis elegans worm has six pairs of chromosomes.

His group studies the cellular and genetic control of gastrulation movements in zebrafish, one of the model organisms studied at the institute besides Drosophila, the C. elegans worm, frogs, mice, and newts.

The Ss - DAF - 12 receptor corresponds to a similar receptor in the long - studied C. elegans worm.

The analysis of different tissues demonstrated MOCOS expression in the brain cells and intestine of several species, and notably the C. elegans worm and mammals.

The C. elegans worm and the Drosophila fruit fly, «the warhorses of developmental biology,» flunk out on this test.

The microscopic Caenorhabditis elegans worm may seem like an odd source of insight into human brain development.

Not exact matches

That's how many lab C. elegans nematodes grow a normal body (left) with a wide, inner feeding tube (partly visible toward worm top).

In findings published today in the journal Cell, postdoctoral fellow Hongyun Tang and Professor Min Han, both of CU Boulder's Department of Molecular, Cellular and Developmental Biology and the Howard Hughes Medical Institute, detail how fat levels in a tiny soil - dwelling roundworm (C. elegans) can tip the balance between whether the worm makes eggs or sperm.

Magnified, the slime comes alive as hundreds of translucent worms, known as Caenorhabditis elegans, slither to and fro.

C. elegans, which contains only 302 neurons, has a natural predator — another worm called Pristionchus pacificus, which bites and kills C. elegans.

Strains of the lab workhorse roundworm C. elegans that lived longer added more time being frail and had the same portion of their lives being healthy as normal worms.

The team at Salk started with a simple creature, the microscopic worm called Caenorhabditis elegans.

Nath is studying sleep in the worm Caenorhabditis elegans, but whenever he presented his work at research conferences, other scientists scoffed at the idea that such a simple animal could sleep.

Researchers studying the nematode worm C. elegans have discovered a new mechanism by which the millimeter - long critter flexes its pooping muscles.

With worms as his subjects, he plumbs the cellular mechanisms driving the complex protein interactions regulating lifespan, some of which — remarkably — have been conserved through evolution all the way from his microscopic Caenorhabditis elegans to us.

Using one of the great advantages of C. elegans, they were able to visualize the influx of calcium that occurred in a neuron in response to stimulus in a living worm.

Already, researchers have used CRISPR / Cas9 to edit genes in human cells grown in lab dishes, monkeys (SN: 3/8/14, p. 7), dogs (SN: 11/28/15, p. 16), mice and pigs (SN: 11/14/15, p. 6), yeast, fruit flies, the worm Caenorhabditis elegans, zebrafish, tobacco and rice.

While completing her postdoc, Murphy began to study C. elegans mutants that could live and reproduce twice as long as normal worms.

To answer this question, Murphy tracked which genes were turned on and off over time in the oocytes and somatic cells in C. elegans IGF - 1 and TGF - β mutants, as well as wild - type worms.

The small worm C. elegans has a set of sensory neurons that detect various conditions in its environment, almost like a sense of smell.

Kenyon works with a millimeter - long worm called Caenorhabditis elegans.

When Murphy compared the genes turned off and on in oocytes and body cells of the same worm, however, she saw that two completely different sets of genes controlled oocyte and body - cell aging in C. elegans.

When Gordon Lithgow at the Buck Institute for Research on Aging in Novato, California, and colleagues grew the soil - dwelling nematode Caenorhabditis elegans in agar plates soaked in thioflavin T — a dye used to visualise clusters of amyloid beta protein — they found that the worms lived 30 to 70 per cent longer than average.

Schafer's team injected DNA that codes for their protein into the gonads of Caenorhabditis elegans nematode worms.

MicroRNAs had been discovered in the worm Caenorhabditis elegans nearly a decade before, but for years most people thought they were junky byproducts of cellular housekeeping.

He presented his idea one day to a roomful of about 30 colleagues at Yale's «Worm Meeting,» the weekly gathering for researchers studying C. elegans, the lowly nematode widely used as a model organism in developmental biology.

But it turns out that we have only about 25,000 genes — about the same number as a tiny flowering plant called Arabidopsis and barely more than the worm Caenorhabditis elegans.

By comparing our genetic make - up to the genomes of mice, chimps and a menagerie of other species (rats, chickens, dogs, pufferfish, the microscopic worm Caenorhabditis elegans, the fruit fly Drosophila melanogaster and many bacteria), scientists have learned a great deal about how genes evolve over time, and gained insights into human diseases.

C. elegans is a microscopic worm that like humans highly expresses a family of proteins in the nervous system called ADARs — adenosine deaminases that act on RNA — a family that includes ADR - 1.

A quirk of the physiology of C. elegans means that such gene inactivation can occur simply if the RNAi molecule is eaten by the worm.

I gave a speech in 1975 that announced that the worm C. elegans was going to open up genetics.

Enormous projects such as ENCODE (for humans and mice) or modENCODE (for other lab model systems, such as the fly Drosophila or the worm C. elegans) have been devoted to collecting these data in order to analyse and interpret them in the framework of genomic data and to form hypotheses about functions and relations.

Next, the scientists tested their hypothesis in the widely studied worm Caenorhabditis elegans, and found that a strain genetically engineered to produce excess amyloid in their guts survived up to 3 days longer after an exposure to Salmonella and yeast than typical worms.

Researchers had previously identified a half - dozen in the worm Caenorhabditis elegans.

Curran and his colleagues tweaked the amount of Maf1 in C. elegans, a transparent worm often used as a model organism by biologists.

As a result, alcohol - exposed worms stop wriggling — the C. elegans version of the sluggish, uncoordinated behavior characteristic of inebriated humans.

Yet when scientists refined it last spring, the count had dropped to little more than 30,000, only a third more genes than a simple worm like Caenorhabditis elegans.

To understand which proteins help meiosis run smoothly, the researchers from Kyoto University's Institute for Integrated Cell - Material Sciences (iCeMS) and Tohoku University in Japan, and Imperial College in London, used a tiny worm known as Caenorhabditis elegans to look into the role of PP4.

«Worms, mice, humans, and even fruit flies show similar effects of intoxication at similar alcohol concentrations,» he says, and human neurons contain a switch similar to that in C. elegans.

«Honestly, I thought I should have gotten in a while ago,» says Cynthia Kenyon of the University of California at San Francisco, whose two decades of research since the 1980s on the developmental biology of the nematode worm Caenorhabditis elegans finally earned her a place in the National Academy.

«Calcium dynamics regulating the timing of decision - making in C. elegans: A tiny worm makes a decision by calculating mathematical integration.»