Sentences with phrase «elements in the human genome»

EPFL scientists have carried out a genomic and evolutionary study of a large and enigmatic family of human proteins, to demonstrate that it is responsible for harnessing the millions of transposable elements in the human genome.

The latest chapter in our story is ENCODE; an ambitious project which aims to characterise all the functional element in the human genome.

One hint came in August, when a team led by biochemist Ramin Shiekhattar at the Wistar Institute in Philadelphia reported that a protein complex responsible for lashing the two copies of each chromosome together just before cell division binds to a repetitive element in the human genome.

ENCODE was created to assemble a comprehensive catalog, or «parts list,» of all functional elements in the human genome.

«We are making great strides in identifying functional elements in the human genome, but we still don't know much about their biological relevance,» said NHGRI Director Francis S. Collins, MD, PhD.

«Our project will serve as a pilot for the full - scale mapping of functional regulatory elements in the human genome,» said program director Kevin White, PhD, the James and Karen Frank Family Professor in the departments of Human Genetics and Ecology & Evolution, and Director of the Institute for Genomics & Systems Biology at the University of Chicago and Argonne National Laboratory.

And now, the ENCODE Consortium has provided us exactly what they promised: an encyclopedia of the functional elements in the human genome.

A second, perhaps less - hyped initiative (called the Encyclopedia of DNA Elements, or ENCODE) set out to delineate all functional elements in the human genome.

The goal of ENCODE is to build a comprehensive parts list of functional elements in the human genome, including elements that act at the protein and RNA levels, and regulatory elements that control cells and circumstances in which a gene is active.

He led the analysis group for the ENCODE project, which is defining functional elements in the human genome.

The findings, published in Nature, reveal millions of new regulatory elements in the human genome that in various ways govern how proteins are formed.

ENCODE was launched in 2003 to identify and characterize the functional elements in the human genome sequence.

Not exact matches

When her appointment came to a close, a colleague rolled his chair over to her one day and suggested her for a data scientist job with the Stanford - based Data Coordination Center of the ENCODE (Encyclopedia of DNA Elements) Consortium, an international collaboration of research groups funded by the National Human Genome Research Institute at the U.S. National Institutes of Health (NIH) in Bethesda, Maryland.

«We explored the opportunity of using sperm RNA elements as a predictor of human health, with applications at the fertility clinic that would go hand - in - hand with the new neonatal intensive care unit genome sequencing to better health outcomes,» said Dr. Krawetz, associate director of the C.S. Mott Center for Human Growth and Develophuman health, with applications at the fertility clinic that would go hand - in - hand with the new neonatal intensive care unit genome sequencing to better health outcomes,» said Dr. Krawetz, associate director of the C.S. Mott Center for Human Growth and DevelopHuman Growth and Development.

The study, the culmination of more than 10 years of research and published online in the journal Arthritis & Rheumatology in June, discovered virus - like elements within the human genome linked to the development of two autoimmune diseases: lupus and Sjogren's syndrome.

The study, «VlincRNAs controlled by retroviral elements are a hallmark of pluripotency and cancer» found that novel non-coding parts of the human genome known as vlincRNAs (very long intergenic, non-coding RNAs) triggered by ancient viruses, participate in the biology of stem cells, and in the development of cancer.

Retrotransposons, the most common type of transposable element in humans, make up about 45 percent of the human genome.

«They have found a smoking gun in the human genome that connects a regulatory element with a proposed pathway for increasing brain size,» says Todd Preuss, a neuroanatomist at the Yerkes National Primate Research Center in Atlanta, who was not involved with the work.

«By means of basic research on model organisms, we are trying to understand human genome instability to identify elements, which, in the future, might be able to be explored as targets of new anti-tumour medicines,» explains the researcher responsible for the project and director of Cabimer, Andrés Aguilera.

This was the most likely reason that ancestral element detection in mouse was so much lower than in human, as the genome - wide substitution rate in mouse is approximately twice that of human.

GRBs (gene regulatory blocks) are regions in the human genome that are enriched for conserved elements.

The polydeoxyadenylate tract of Alu repetitive elements is polymorphic in the human genome.

The National Human Genome Research Institute, part of the National Institutes of Health, has awarded $ 9.1 million over four years to a research team led by the University of Chicago to identify all regulatory elements, the DNA sequences that control when and where specific genes get turned on or off, in the fruit fly gGenome Research Institute, part of the National Institutes of Health, has awarded $ 9.1 million over four years to a research team led by the University of Chicago to identify all regulatory elements, the DNA sequences that control when and where specific genes get turned on or off, in the fruit fly genomegenome.

Scientists at Penn State College of Medicine, working alongside an international team of researchers, have produced the most complete encyclopedia of functional elements in the mouse genome to date and compared it to the human genome.

We focus on developing computational methods and tools for (a) analyzing large - scale gene expression data related to human cancer in search for gene markers and disease sub-categories, (b) identifying regulatory elements such as miRNA precursors and their targets in whole genomes of plants and mammals, (c) building theoretical models of gene regulatory networks.

We report here a significant improvement in the resolution of array CGH, with the development of an array platform that utilizes single - stranded DNA array elements to accurately measure copy - number changes of individual exons in the human genome.

Gerstein is one of hundreds of researchers who participated in ENCODE, or the Encyclopedia of DNA Elements, a massive collaboration launched in 2003 to catalogue the human genome's every last piece.

The ENCODE maps allow researchers to inspect the chromosomes, genes, functional elements and individual nucleotides in the human genome in much the same way.»

Recent studies indicate that long interspersed nuclear element - 1 (L1) are mobilized in the genome of human neural progenitor cells and enhanced in Rett syndrome and ataxia telangiectasia.

The DAXX co-repressor is directly recruited to active regulatory elements genome - wide to regulate autophagy programs in a model of human prostate cancer

Only a minority of RNAs transcribed in a human cell goes on to template protein production, according to a 2007 assessment of the human genome by the Encyclopedia of DNA Elements (ENCODE) Project Consortium, which was funded by the National Human Genome Research Instihuman cell goes on to template protein production, according to a 2007 assessment of the human genome by the Encyclopedia of DNA Elements (ENCODE) Project Consortium, which was funded by the National Human Genome Research Instihuman genome by the Encyclopedia of DNA Elements (ENCODE) Project Consortium, which was funded by the National Human Genome Research Instgenome by the Encyclopedia of DNA Elements (ENCODE) Project Consortium, which was funded by the National Human Genome Research InstiHuman Genome Research InstGenome Research Institute.

In their new study published in Cell, the team investigated enhancers containing «ultraconserved elements,» which are at least 200 base pairs in length and are 100 percent identical in the genomes of humans, mice and ratIn their new study published in Cell, the team investigated enhancers containing «ultraconserved elements,» which are at least 200 base pairs in length and are 100 percent identical in the genomes of humans, mice and ratin Cell, the team investigated enhancers containing «ultraconserved elements,» which are at least 200 base pairs in length and are 100 percent identical in the genomes of humans, mice and ratin length and are 100 percent identical in the genomes of humans, mice and ratin the genomes of humans, mice and rats.

The National Human Genome Research Institute (NHGRI), part of the National Institutes of Health, today announced approximately $ 31.5 million in grants this fiscal year, pending funds, as part of its latest expansion of the Encyclopedia of DNA Elements (ENCODE) project, or ENCODE 4.

Only an estimated 10 % of RNAs transcribed in a human cell go on to template proteins, according to a 2007 assessment of the human genome by the Encyclopedia of DNA Elements (ENCODE) Project Consortium, which was funded by the National Human Genome Research Instihuman cell go on to template proteins, according to a 2007 assessment of the human genome by the Encyclopedia of DNA Elements (ENCODE) Project Consortium, which was funded by the National Human Genome Research Instihuman genome by the Encyclopedia of DNA Elements (ENCODE) Project Consortium, which was funded by the National Human Genome Research Instgenome by the Encyclopedia of DNA Elements (ENCODE) Project Consortium, which was funded by the National Human Genome Research InstiHuman Genome Research InstGenome Research Institute.

Termed «ultraconserved elements» or UCEs, these portions of the genome have remained unchanged for 300 to 500 million years, appearing in the same state across multiple animal species — from humans to dinosaurs to platypuses.