Sentences with phrase «elephant cells»

The Harvard - based team, led by Dr. George Church, is currently using CRISPR genome engineering to copy - and - paste DNA from the mammoth genome into living elephant cell cultures (fibroblasts).

«Forty - five mammoth genes in elephant cells, more than 4000 to go!»

They found that elephant cells exposed to radiation self - destruct at twice the rate of healthy human cells and more than five times the rate of Li - Fraumeni cells (14.6 %, 7.2 %, and 2.7 %, respectively).

In isolated elephant cells, this activity is doubled compared to healthy human cells, and five times that of cells from patients with Li - Fraumeni Syndrome, who have only one working copy of p53 and more than a 90 percent lifetime cancer risk in children and adults.

Duplications of the p53 gene makes elephant cells more likely to die in response to DNA damage, rather than turn cancerous

A year before that, in 2014, Church told a large group of science writers that his lab was close to making «organoids» of genetically modified elephant cells:

Already, news of mammoth genes cloned in living elephant cells has emerged from two research groups this year.

Lynch and his colleagues are now identifying candidates for other mammoth genes to functionally test as well as planning experiments to study mammoth proteins in elephant cells.

According to Church, his laboratory has so far put 45 DNA edits into elephant cells:

Schiffman and his team conducted another series of experiments in the laboratory on blood samples from adult African elephants to find how these genes respond to DNA damage in the elephant cells.

The Harvard Woolly Mammoth Revival team headed by George Church (the Church Lab) is working to identify cold climate adapted alleles of the mammoth genome and edit them into living elephant cells.

Last year, George Church and his postdocs at Harvard moved 16 genes governing 3 mammoth traits (long hair, subcutaneous fat, and cold - adapted hemoglobin) into living elephant cells.