Mice homozygous for the obese spontaneous mutation, Lepob (commonly referred to as ob or ob / ob), exhibit obesity, hyperphagia, transient hyperglycemia, glucose intolerance, and
elevated plasma insulin.
Not exact matches
She found that
elevated body mass index,
elevated fasting
insulin,
insulin resistance and, especially,
elevated fasting
plasma glucose in the pre-diabetic range, were all predictors of insufficient milk supply in women attempting to exclusively breastfeed.
Fructose - induced in vivo
insulin resistance and
elevated plasma triglyceride levels in rats.
Hepatic IR ensues, increasing endogenous glucose production, hence
elevating plasma glucose levels and stimulating further
insulin secretion.
These results concur with previous data indicating that only moderate
insulin elevations (15 — 30 mU / L) are required to maximize net muscle protein balance in the presence of
elevated plasma amino acids [96].
Lactate, which increases during starvation, can induce hepatic ketogenesis.2 Low - carbohydrate, fat - rich meals can enhance alpha - cell secretion of glucagon and lower
insulin concentrations.3, 4
Plasma fatty acid concentrations can be twice as high during low - carbohydrate diets as compared with the usual carbohydrate intake in the postabsorptive period.5 Increased concentrations of free fatty acids in the absence of carbohydrate - induced inhibition of beta - oxidation of fatty acids and in the presence of an abnormally high ratio of glucagon to
insulin and
elevated concentrations of lactate may have caused ketoacidosis in our patient, who was trying to avoid all dietary carbohydrates.