Sentences with phrase «elicited similar increases»

Not exact matches

We observed similar robust increases of intracellular calcium concentrations in response to KCl and ATP in both GFP - expressing (n = 28) and GFP - nonexpressing cells (n = 12), whereas 5 - HT elicited an increase in intracellular calcium only in GFP - expressing cells (KCl: t (40) = 0.98, p = 0.33; ATP t (38) = 1.04, p = 0.30; 5 - HT: t (38) = 5.24, p < 0.0001 Student's t tests; Fig. 4A, B, F).

The increase in intracellular NAD elicited by CD38 deletion significantly activated SIRT1 and prompted clinical phenotypes similar to those expected for SIRT1 activation, including protection against diet - induced obesity and a robust deacetylation of SIRT1 targets.

In a second study, Pikosky et al. (16) demonstrated negative nitrogen balance in healthy young volunteers in response to a 7 - d period of negative energy balance (− 4184 kJ / d or − 1000 kcal / d) elicited solely by an increase in aerobic - type physical activity when protein was consumed at levels similar to the current RDA (0.9 g · kg − 1 · d − 1).