INFLAMMATORY BOWEL DISEASE (IBD) The inflammatory bowel diseases (IBD) are the most common causes of chronic vomiting and diarrhea in dogs, and refer to a group of idiopathic, chronic gastrointestinal tract disorders, characterized by infiltration of the lamina propria by lymphocytes,
plasma cells, eosinophils, macrophages, neutrophils, or combinations of these
cells.12 The diagnosis of IBD requires the comprehensive exclusion of potential causes of gastrointestinal inflammation, including intestinal parasites, small intestinal bacterial overgrowth, bacterial enterocolitis, dietary intolerances or allergies, and neoplasia.12 Failure to
eliminate known causes of gastrointestinal inflammation which can mimic IBD can result in frustration for the owner and clinician due to poor responsiveness of the animal to dietary or pharmacologic therapy.
Special Areas of Interest: Osteosarcoma,
plasma cell tumors, lymphoma, mast
cell tumors, and investigating ways in which the immune system can be modified to better recognize and
eliminate cancer
cells.