Sentences with phrase «embryonic cell types»

By contrast, most embryonic and induced pluripotent stem cells are more restricted in their developmental potential, able to form embryonic cell types, but not extra-embryonic tissues.

«We were interested in the origins of lamprey gut neurons because in other vertebrates they arise from a particular embryonic cell type, called neural crest cells,» says Stephen Green, postdoctoral scholar in biology and biological engineering and co-first author on the paper.

Not exact matches

Embryonic stem cells are scientifically and medically interesting because they are «pluripotent» (capable of generating many cell types), but they are not the same as totipotent single - cell embryos.

However, embryonic stem cells remain the «gold standard,» and studies of all types of stem cells should continue in parallel for the foreseeable future.»

Embryonic cells are pluripotent, having the full genetic code enabling them to become any type of cell; they differentiate into particular cells in their later development.

It made the front page of the New York Times, but don't let that dissuade you ¯ reports today about new ethical sources of embryonic - type stem cells are credible, and they are very good news.

Not that a principled moral objection shouldn't be enough, but, for those sitting on the fence, the additional discoveries of alternative sources of embryonic - type stem cells should be decisive.

She says, «Our new findings show that in the absence of embryonic movement the cells that should form articular cartilage receive incorrect molecular signals, where one type of signal is lost while another inappropriate signal is activated in its place.

«Our new findings show that in the absence of embryonic movement the cells that should form articular cartilage receive incorrect molecular signals, where one type of signal is lost while another inappropriate signal is activated in its place,» Paula Murphy, a professor of zoology at Trinity College Dublin who co-led the study, says.

From the embryonic stem cells, the researchers produced a type of tissue called retinal pigment epithelium (RPE).

The researchers detected this SMN long noncoding RNA, or lnc - RNA (pronounced «link RNA») for short, in human embryonic kidney cells, brain cell samples and neurons derived from the stem cells of healthy people and those with spinal muscular atrophy type I and II.

Instead, after several days, researchers harvest embryonic stem cells, which theoretically can develop into any type of cell and, according to many researchers, may someday be used to treat neurodegenerative diseases or other conditions.

Furthermore, by making use of embryonic stem cells and in vitro differentiation, SIF - seq can be used to assess enhancer activity in a wide variety of disease - relevant cell types.»

A type of «virgin birth» stem cell could be as powerful as embryonic stem cells but without the same ethical objections, and are being tested for Parkinson ’s

Trials of cells made from human embryonic stem cells are also poised to begin in people with type 1 diabetes and heart failure, the first time embryonic stem cells have been used in the treatment of major lethal diseases.

Decades after they were discovered, human embryonic stem cells are being trialled as a treatment for two major diseases: heart failure and type 1 diabetes

«We've shown that SIF - seq can be used to identify enhancers active in cardiomyocytes, neural progenitor cells, and embryonic stem cells, and we think that it has the potential to be expanded for use in a much wider variety of cell types,» Dickel says.

Further ahead, he is looking to an emerging technology known as induced pluripotent stem cells (iPSCs), in which adult cells are reprogrammed to be like embryonic stem cells so they can transform into any type of cell.

Induced pluripotent stem cells (known as iPSCs) are similar to human embryonic stem cells in that both cell types have the unique ability to self - renew and have the flexibility to become any cell in the human body.

Using a mathematical model known as the Ising model, invented to describe phase transitions in statistical physics, such as how a substance changes from liquid to gas, the Johns Hopkins researchers calculated the probability distribution of methylation along the genome in several different human cell types, including normal and cancerous colon, lung and liver cells, as well as brain, skin, blood and embryonic stem cells.

Some of the researchers at the centre will study the differentiation of stem cells into other cell types, one group by using human embryonic stem cell biology and another by studying early embryo development.

Embryonic stem cells are pluripotent, able to create all cell types, save more embryoniEmbryonic stem cells are pluripotent, able to create all cell types, save more embryonicembryonic tissue.

The newly discovered human cells, named «cord - blood - derived embryonic - like stem cells» or CBEs, are not quite as primitive as embryonic stem cells, which can give rise to any tissue type of the body.

ERRORS have occurred in a type of stem cell that could be used instead of embryonic stem cells — and in tissues made from them.

In the latest study, the researchers hypothesize that the downregulation of these three genes reprograms the cells so that they return to an embryonic - like state, in which they have the potential to give rise to a number of different cell types.

Two types of stem cells were used to produce the mini-brains: embryonic cells and adult cells that had been reprogrammed to a starter state.

(Embryonic stem cells are notable because they can morph into virtually any cell type in the body.)

Semenza says methylation leads to the destruction of NANOG's mRNA so that no protein is made, which in turn causes the embryonic stem cells to abandon their stem cell state and mature into different cell types.

These factors guide a reprogramming process that reverts the cells to an embryonic state, in which they have the potential to become virtually any type of cell.

All stem cells are immature cells known for their ability to multiply indefinitely and give rise to progenitor cells that mature into specific cell types that populate the body's tissues during embryonic development.

Although primed, post-implantation embryonic stem cells can still turn into any type of human cell, they are more difficult to work with than the pre-implantation, naive cells.

Embryonic stem cells: They can turn into any of the body's 220 different cell types, meaning they are pluripotent.

Each of these cells, called naive, pre-implantation embryonic cells, has the capacity to develop into any cell type in the human body, an ability called pluripotency.

Using a nuclear protein expressed in follicle stem cells (FSCs), the researchers found that castor, which plays an important role in specifying which types of brain cells are produced during embryonic development, also helps maintain FSCs throughout the life of the animal.

Since embryonic stem cells can differentiate into any type of tissue, they have the potential to treat an almost unending array of medical conditions — replacing damaged or lost body parts or tissues, slowing degenerative diseases, even growing new organs.

But they still want to be able to do cloning, otherwise know as somatic cell nuclear transfer (SCNT), because embryonic cells are the «gold standard» for pluripotent cells — cells that can become any cell type in the body.

In the last few years, researchers have learned how to turn embryonic stem cells into all sorts of different cell types, such as skin cells, heart

The results help fill in the scientific puzzle kicked off by Dolly's cloning, which proved that mammalian egg cells were capable of dissolving the genetic roadblocks that limit the potential of most adult cells to give rise to only a single type of tissue — that of the organ from which they hail — whereas embryonic stem cells have the potential to become virtually any kind of body tissue.

«The beautiful thing,» Lanza says, «is that if you have an embryonic stem cell line that is O negative, because it's immortal you could create an unlimited amount of universal blood that would match virtually everybody, so you wouldn't have to worry about matching blood types.»

In contrast to embryonic stem cells, when adult stem cells divide, their offspring are only able to develop at the same site and in certain tissue types.

«Embryonic stem cells are pluripotent, meaning they have the ability to become any type of tissue,» Fuchs says.

But even more far - ranging treatments may be possible with embryonic stem cells, the blank - slate cells that give rise to all organs and tissue types and that (theoretically) can repair all forms of organic damage and disease.

The remarkable discovery that it is possible to turn skin cells back to an embryonic state, when they have the potential to become any type of cell in the body, could open up a huge range of possibilities.

Because biologists like Daley are convinced that embryonic stem cells — the most generic, versatile type — may not only lead to dramatically different new treatments but can also uniquely illuminate the origins of disease in a way adult stem cells never will.

«Use of induced pluripotent stem cell (iPSC) technology» — which involves taking skin cells from patients and reprogramming them into embryonic - like stem cells capable of turning into other specific cell types relevant for studying a particular disease — «makes it possible to model dementias that affect people later in life,» says senior study author Catherine Verfaillie of KU Leuven.

There is evidence that chronic disabilities such as spinal cord lesions, diabetes, and Parkinson?s disease, where replacement of just one cell type restores tissue function, can be treated with differentiated embryonic stem cells.

«Genetically, this type of clone is still a member of our species,» says David Prentice, a cellular biologist at Indiana State University and cofounder of Do No Harm, a group of scientists favoring alternatives to embryonic stem cell research.

These stem cells, which are similar to highly sought - after embryonic stem cells but derived from adult cells and then reprogrammed, could be turned into the cell types needed for research, including neurons and intestinal and fat cells.

The researchers discovered that this region is required to both turn Sox2 on, and for the embryonic stem cells to maintain their characteristic appearance and ability to differentiate into all the cell types of the adult organism.

Mature embryonic stem cells cultivated in the laboratory can, under the right conditions, be backed up in their development to the more immature stem cell type.