It is possible that in
embryonic development similar sorts of ordering are at least initiated by chemical gradients (see LEC).
Not exact matches
In a
similar way to how they work in other cells, epigenetic markers push PGCs to their fate during
embryonic development, but PGCs are unique because when they develop into sperm and eggs, the epigenetic markers are erased.
«We do not yet know whether a protein with a
similar function also plays a role in human
embryonic development, but we suspect so,» says Buchner.
The next step, he says, is to investigate how
embryonic mouse brains with induced folds develop as they mature past the fetal stages of
development and to look across species to see if the gene has
similar effects in other mammals.
This migration may happen because the repair pathways initiated by the damaged cells are
similar to pathways triggered during
embryonic development, where stem cells are key, explains ReNeuron co-founder and chief scientific officer John Sinden.
The mechanisms that underlie early
embryonic development in humans and cattle are very
similar.
In a
similar manner, the induction of hematopoietic (cluster 20, day 3.5 +4 = E7.5) and cardiovascular - specific (cluster 12, 3.5 +5 = E8.5) genes follows the chronological order of the appearance of blood islands and the formation of the heart tube during
embryonic development [50], [51].