Sentences with phrase «embryonic heart»

A molecular switch that seems to be essential for embryonic heart cells to grow into more mature, adult - like heart cells has been discovered.

Another gene active in the peduncle is related to one that, in higher organisms, functions prominently in embryonic heart tissue.

In laboratory experiments with mice that had experienced a heart attack, Drs. Qian and Srivastava delivered three genes that normally guide embryonic heart development — together known as GMT — directly into the damaged region.

These genes normally guide embryonic heart development; however, in the adult mice hearts, they helped transform non-beating cells that form scar tissue into beating heart muscle cells.

Deepak Srivastava and his team at the Gladstone Institute of Cardiovascular Disease in San Francisco created mouse cardiomyocytes by exposing mouse fibroblasts to three transcription factor proteins that activate genes needed for the formation of embryonic heart tissue.

New research from a team including Carnegie's Daniel Gorelick and Marnie Halpern on the effects of these chemicals on zebrafish shows that embryonic heart valves could be particularly in danger.

Because the blood in the 150 - micrometer - long embryonic heart is so viscous, the speed and turbulence of the blood causes the vessel walls to experience a high shear stress — like a skateboarder would experience upon falling and sliding across pavement.

SAN FRANCISCO, CA — Scientists at the Gladstone Institutes have revealed the precise order and timing of hundreds of genetic «switches» required to construct a fully functional heart from embryonic heart cells — providing new clues into the genetic basis for some forms of congenital heart disease.

Since the signalling mechanisms affected in these diseases are the same mechanisms that occur during embryonic heart development, their study is a subject of great interest and relevance.

Embryos from the folic acid diet MTHFR + / + group were delayed and the folic acid diet was associated with thinner ventricular walls in embryonic hearts.

WHEN the embryonic heart begins to beat, it kick - starts the production of blood from cells lining the growing aorta, two independent research teams have shown.

MBNL proteins regulate the switch from exon 6A in embryonic heart to exon 6B in adult.

The investigators found that the helpful macrophages originate in the embryonic heart and harmful macrophages originate in the bone marrow and could be distinguished by whether they express a protein on their surface called CCR2.

What we found is that cardiac precursor cells that are present in the embryonic heart do indeed give rise to components of the heart in adults but also give rise to the blood cells.»

That's obvious, but the converse also appears to be true: Without flowing blood, the beating heart can not grow and develop properly, according to a new study that measures and manipulates the fluid forces on the vessel walls of the embryonic heart.

According to new research led by scientists at The Salk Institute, the vitamin plays a critical role in helping to guide the embryonic heart to its final destination in the left side of the body of all vertebrates, including humans.

It has been suggested that cardiac fibroblasts, which are cells that surround the muscle cells and make up over half of the heart cells, might be important in embryogenesis, but little is known about their development and roles in the embryonic heart.

In the adult mouse (Fig. 4c) PRDM16 expression was somewhat reduced overall compared to the embryonic heart but was still predominantly localized to the nuclei of cardiomyocytes.

Ultrasound may be used to confirm pregnancy much earlier (after 25 days, the embryonic heart may be seen beating) but it is more difficult to count the number of pups using this method.