Sentences with phrase «embryonic heart cells»

SAN FRANCISCO, CA — Scientists at the Gladstone Institutes have revealed the precise order and timing of hundreds of genetic «switches» required to construct a fully functional heart from embryonic heart cells — providing new clues into the genetic basis for some forms of congenital heart disease.

A molecular switch that seems to be essential for embryonic heart cells to grow into more mature, adult - like heart cells has been discovered.

Not exact matches

In a study in the journal Science, researchers explain how they used mouse embryonic stem cells and microchip technology to create heart muscle tissue that actually beats.

Human embryonic stem cells are at last being tested in common, potentially fatal diseases such as heart failure and diabetes

Trials of cells made from human embryonic stem cells are also poised to begin in people with type 1 diabetes and heart failure, the first time embryonic stem cells have been used in the treatment of major lethal diseases.

Decades after they were discovered, human embryonic stem cells are being trialled as a treatment for two major diseases: heart failure and type 1 diabetes

Two weeks after the experimental myocardial infarctions, the Seattle researchers injected 1 billion heart muscle cells derived from human embryonic stem cells, called human embryonic stem cell - derived cardiomyocytes, into the infarcted muscle.

The results of the experiment appear in the April 30 advanced online edition of the journal Nature in a paper titled, «Human embryonic - stem cell derived cardiomyocytes regenerate non-human primate hearts.»

«Although we can now induce embryonic stem cells to become heart cells, getting them to mature to an adult - like state remains a significant challenge,» said Hannele Ruohola - Baker, University of Washington professor of biochemistry and senior author of the paper.

In the last few years, researchers have learned how to turn embryonic stem cells into all sorts of different cell types, such as skin cells, heart

Mice generated from embryonic stem cells in which ion channel genes have been mutated by homologous recombination often have a perfectly normal heart.

The result — the second such finding in the past year — suggests that similar cells from human testicles might have similar powers, paving the way to creating replacement tissue for men who have suffered damage from heart attacks or other injuries and avoiding some of the controversy surrounding embryonic stem cells (ESC).

Last December, for instance, Chien's group reported finding markers for heart muscle stem cells by tracing their development from embryonic tissue.

(Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts Nature Biotechnology)

A fix for broken rat hearts Scientists this week successfully implanted human embryonic stem cells into rats that suffered heart attacks, coming a heartbeat closer to realizing the full potential of such therapy.

Specifically, the researchers generated the tissue from human embryonic stem cells with the resulting muscle having significant similarities to human heart muscle.

What we found is that cardiac precursor cells that are present in the embryonic heart do indeed give rise to components of the heart in adults but also give rise to the blood cells.»

The potential of iPS cells to help treat everything from damaged heart tissue to Parkinson's disease, has prompted intensive research that has looked into the use of skin fibroblast cells as an alternative to controversial embryonic stem cells.

Researchers at the Stanford University School of Medicine have mapped out the sets of biological and chemical signals necessary to quickly and efficiently direct human embryonic stem cells to become pure populations of any of 12 cell types, including bone, heart muscle and cartilage.

Then there are stem cells, which tantalize with their myriad possibilities: allowing diabetics to throw away their insulin, growing healthy cardiac tissue after a heart attack, restoring function to people with spinal cord injury (for which the Food and Drug Administration just approved the first embryonic stem cell trial).

Formation of Human Myocardium in the Rat Heart from Human Embryonic Stem Cells.

«Discovery of a gene that could convert human embryonic stem cells into myocardial cells would be golden,» said Didier Stainier, PhD, UCSF assistant professor of biochemistry and biophysics, the senior author of the UCSF study and a pioneer in the study of heart development in the transparent zebrafish embryo.

Scientists at the Gladstone Institutes have discovered how to make a new type of cell that is in between embryonic stem cells and adult heart cells, and that may hold the key to treating heart disease.

CDI is currently supplying embryonic stem cell - derived heart cells to California - based Roche and other pharmaceutical companies for drug screening, and hopes to create other cell types in the future.

Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat heart.

A human embryonic stem cell is reined in — prevented from giving up its unique characteristics of self - renewal and pluripotency — by the presence of a protein modification that stifles any genes that would prematurely instruct the cell to develop into heart or other specialized tissue.

5/15/2008 New Role Found for a Cardiac Progenitor Population In a discovery that could one day lead to an understanding of how to regenerate damaged heart tissue, researchers at the University of California, San Diego have found that parent cells involved in embryonic development of the epicardium — the cell l...

They found that groups of genes appear to work together in heart cells in a coordinated fashion — switching on and off as a group at designated times during embryonic development.

Embryonic stem cells with identical genomes grow into distinctive tissues, such as heart, bone, and brain.

They have injected stem cells (adult, embryonic) into mice with damaged hearts.

Human embryonic stem cells have the remarkable capacity to mature into all of the 200 kinds of cells that make up the human body: skin, bone, nerve, blood, heart, and so on.

InvivoSciences makes engineered heart tissues from mouse embryonic stem cells and stem cells from differentiated adult tissues in humans, such as fat and skin.

Co-culture of embryonic chick heart cells and ciliary ganglia induces parasympathetic responsiveness in embryonic chick heart cells

Thomson still supports lifting Bush's restrictions, he said, because no one knows whether the new iPS cells can match embryonic cells» knack for growing into any kind of tissue — brain cells, heart muscle, insulin - producing cells and dozens of others — in mass quantities.

During that time, she applied her knowledge of the processes governing normal heart development to direct the differentiation of embryonic stem cells into the cardiac lineage.

These genes normally guide embryonic heart development; however, in the adult mice hearts, they helped transform non-beating cells that form scar tissue into beating heart muscle cells.

As you know, embryonic stem cells have the potential to be used to treat and better understand deadly and disabling diseases and conditions that affect more than 100 million Americans, such as cancer, heart disease, diabetes, Parkinson's, Alzheimer's, multiple sclerosis, spinal cord injury, and many others.

But initial experiments on human fibroblasts from three sources — fetal heart cells, embryonic stem cells and neonatal skin cells — revealed that the GMT combination alone was not sufficient.

Researchers announced they mimicked the way embryonic stem cells develop into heart muscle in a lab.