Sentences with phrase «embryonic kidney»
The phrase "embryonic kidney" refers to a developing or growing kidney in the early stages of an organism's life. Full definition
Thus, upon activation by ActD, AKT becomes an inducer of p53 tumor suppression instead of being a survival factor, as consistently shown in human embryonic kidney cell lines (293 and 293T), human hepatoma cell line (HepG2), and mouse hepatoma cell line (Hepa - 1c1c7).
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By transferring the gene for melanopsin into human embryonic kidney cells, synthetic biologist Martin Fussenegger of the Swiss Federal Institute of Technology in Zurich and colleagues made these cells light - sensitive as well.
Martin Fussenegger and colleagues at the Swiss Federal Institute of Technology in Zurich created biological versions of two key digital circuits inside two sets of embryonic kidney cells: a half adder and half subtractor.
«Our data suggest that when Lin28 is active for too long, it keeps the kidneys from completing their developmental program, which would explain Wilms tumors» resemblance to embryonic kidney tissues» says Urbach, a former Boston Children's researcher, who is now on the faculty of Bar - Ilan University in Israel.
When examined under a microscope, the tumors resemble immature embryonic kidneys, leading doctors to conclude that Wilms tumors form when kidney development, normally complete by birth, persists into childhood.
Derived mostly from human embryonic kidney 293T (HEK293T) and HeLa cell lines, EdiGene Knockout (KO) Cell Lysates have been optimized through the use of genome editing technology and validated at the genomic level through PCR and Sanger - sequencing techniques to ensure the accuracy and knockout of the target gene.
The researchers also demonstrated the adaptation of this strategy to kidney bud formation using embryonic kidney cells, and resulted in the formation of integrated glomerular - like tissues after transplantation.
HuH - 7 (human HCC), HepG2 (human hepatocellular blastoma), 293T (human embryonic kidney fibroblast), HeLa (human cervical cancer cells), NIH 3T3 (murine fibroblast), and HCT116 (human colon cancer) and its derived cell line HCT116 p21 − / − (kindly provided by Dr. B. Vogelstein, Howard Hughes Medical Institute, Chevy Chase and the Sydney Kimmel Comprehensive Cancer Center of the Johns Hopkins University School of Medicine, Baltimore, MD; ref.
Retroviral vectors containing cDNAs for OCT3 / 4 and KLF4 were obtained from Addgene (Cambridge, MA) and transfected, along with packaging plasmids CMV Gal - Pol and VSVG, into human embryonic kidney carcinoma 293 cells (HEK - 293) using the CaCl2 transient transfection method.
N - Acetylcysteine Amide (NACA) Reduces Cell Death after Oxidative Stress in a Porcine Embryonic Kidney Cell Line
Before toying with worms, the S.U.N.Y. Buffalo team tried out their technique on cultures of human embryonic kidney cells and neurons from a rat hippocampus, a part of the brain integral to memory.
The researchers detected this SMN long noncoding RNA, or lnc - RNA (pronounced «link RNA») for short, in human embryonic kidney cells, brain cell samples and neurons derived from the stem cells of healthy people and those with spinal muscular atrophy type I and II.
Fussenegger created his biological calculator by engineering an embryonic kidney cell to respond to two different chemicals: erythromycin (an antibiotic) and phloretin (a compound found in apple trees).
Endocytosis of Frizzled 4 (Fz4) in human embryonic kidney 293 cells was dependent on added Wnt5A protein and was accomplished by the multifunctional adaptor protein β - arrestin 2 (βarr2), which was recruited to Fz4 by binding to phosphorylated Dvl2.
Human lung epithelial cells and human embryonic kidney cells were exposed to several viruses, Ebola virus, Marburg virus, vesicular stomatitis virus and Zika virus, and the antiviral effects of the three chemical structures were observed.
The researchers determined from cultures of human embryonic kidney cells that lower caloric intake sends a signal that activates a gene inside cells that codes for the enzyme NAMPT (nicotinamide phosphoribosyltransferase).
We then coax a cell line made from an embryonic kidney into taking up the Trojan horse plasmid.
Similar results were obtained when the toxicity of niclosamide and oxyclozanide were evaluated against HEK293 human embryonic kidney cells [35, 36].
Human embryonic kidney (HEK) 293T cells, a packaging cell line for lentivirus production, and the preosteoclast cell line RAW264.7 (ATCC) were maintained in DMEM supplemented with 10 % FBS and antibiotics.
293 is a human embryonic kidney cell line, and 293T is a derivative of 293 cells with an expression of SV40 T antigen.
Human embryonic kidney (HEK) 293T cells, and MCF7, and MDA - MB - 231 breast carcinoma cells were maintained in Dulbecco's modified Eagle's medium (DMEM) with 10 % FBS, 100 U / ml penicillin, 100 μg / ml streptomycin with or without 250 ng / ml amphotericin B (Invitrogen, Carlsbad, CA) and incubated at 5 % CO2 at 37 °C.
Human embryonic kidney cells were transfected with Flag - tagged human Gasp, and lysates from these cells were immunoprecipitated with anti-Flag antibody.