Sentences with phrase «embryonic mouse stem»

Now Yoshiki Sasai of the RIKEN Center for Developmental Biology in Kobe, Japan, and his colleagues have induced embryonic mouse stem cells to spontaneously form the optic cup in a dish.

Not exact matches

In a study in the journal Science, researchers explain how they used mouse embryonic stem cells and microchip technology to create heart muscle tissue that actually beats.

The ability of SIF - seq to use reporter assays in mouse embryonic stem cells to identify human embryonic stem cell enhancers that are not present in the mouse genome opens the door to intriguing research possibilities as Dickel explains.

The scientists rescued the microcephaly during mouse embryonic development by removing a protein that caused the loss of stem cells.

The study results were found using mouse embryonic stem cells, which are good cell models for the study of processes seen in human stem cells.

During the next 3 years, Lexicon will put high - throughput robots to work generating 500,000 mutant mouse embryonic stem - cell clones.

Base oxidation regulates gene activity In cooperation with colleagues at LMU, as well as researchers based in Berlin, Basel and Utrecht, Carell and his group have now shown, for the first time, that a standard base other than cytosine is also modified in embryonic stem cells of mice.

The team inserted this «magnet» into mouse embryonic stem cells, next to a gene that promotes a protein called p16.

During embryonic development of mice, however, the situation is different: To build up the system, all mature blood and immune cells develop much more rapidly and almost completely from stem cells.

The team also found that ERAS, a tumorigenic gene expressed in mouse embryonic stem cells and iPSCs, was mutated and dysfunctional in the mole - rat iPSCs.

Scientists, with practice, have now been able to make nuclear transfer nearly routine to produce cattle, cats, mice, sheep, goats, pigs, and — as a Korean team announced in May — even human embryonic stem (ES) cells.

The only previous demonstration — by researchers led by Shou - Wei Ding, PhD, a professor of Plant Pathology and Microbiology at UC Riverside and co-corresponding author of the current study — was done in embryonic stem cells and in newborn mice.

In collaboration with Ding, the lab of Olivier Voinnet at the Swiss Federal Institute of Technology in Zurich also reported in an accompanying paper the detection of viral siRNAs in cultured mouse embryonic stem cells infected by the Encephalomyocarditis virus.

The research team used mass spectrometry to compare phosphorylation of proteins from mouse embryonic stem cells with fully functioning GSK - 3 to cells in which the gene encoding GSK - 3 had been deleted.

Mouse embryos: Scientists first found embryonic stem cells in mice in the 1970s, but an understanding of the critical role they play in cell differentiation only emerged years later.

Now you know that if you take a mouse embryonic stem cell that is, say, labeled so all of the developed cells will be blue, and you inject it into a mouse blastocyst, you'll get a chimera.

The paper doesn't include any genetic analysis of the final eggs that confirms they are healthy, notes Mitinori Saitou, a stem cell biologist at Kyoto University in Japan whose team developed methods to create mouse egg cells from embryonic or reprogrammed stem cells.

Starting in the mid-2000s, Yoshiki Sasai's team at the RIKEN Center for Developmental Biology in Kobe, Japan, demonstrated how to grow brainlike structures using embryonic stem cells, first from mice and then humans.

The scientists first compared mouse megakaryocyte cells created from embryonic stem cells engineered to lack p45 - Nfe2 with normal megakaryocytes.

EYE CANDY Researchers grew primitive retinas (one shown, with proteins that collect and transmit light signals in green and red) by embedding mouse embryonic stem cells in a gel.

In the past few months, researchers in the United States and Japan have described a promising way of deriving embryonic stem cells from skin cells (of mice) without destroying embryos — the «Holy Grail of biotechnology,» as The Times of London put it.

• A team led by Ron McKay at the National Institute of Neurological Disorders and Stroke in Bethesda, Maryland, turned mouse embryonic stem cells into isletlike cells, another step down the long road to a cure for diabetes.

Beginning with mouse egg cells, Daley and his team tricked these egg cells, or oocytes, into thinking they had been fertilized (a process called parthenogenesis) and managed to isolate embryonic stem cells from the subsequent early mouse embryos.

Mouse embryonic stem cells, reported in 1981 by Martin Evans, Matthew Kaufman, and Gail Martin, have allowed scientists to generate genetically customized strains of mice that have revolutionized studies of organismic development and immunity and have provided countless models of human disease.

Mice generated from embryonic stem cells in which ion channel genes have been mutated by homologous recombination often have a perfectly normal heart.

Using mouse embryonic stem cells that generate motor neurons as a model, the researchers found that CTCF isolates Hox genes from harmful activation.

Prior to joining GE, Dr. Hagner - McWhirter was a postdoctoral researcher at Uppsala University working with mouse embryonic stem cells.

The researchers confirmed Olig2's role in promoting motor neuron formation by increasing or blocking the function of Olig2 in the spinal cords of developing mouse and chicken embryos, as well as during motor neuron formation in mouse embryonic stem cells.

Renee Reijo Pera, a biologist at Stanford's Institute for Stem Cell Biology and Regenerative Medicine, points out that earlier attempts to create offspring with sperm from embryonic stem cells resulted in short - lived mouse pups that were either giants or midgStem Cell Biology and Regenerative Medicine, points out that earlier attempts to create offspring with sperm from embryonic stem cells resulted in short - lived mouse pups that were either giants or midgstem cells resulted in short - lived mouse pups that were either giants or midgets.

Working with mouse embryonic stem cells (mESCs), scientists at the IBS Center for RNA Research have come one step closer to understand how to control induced pluripotent stem cells.

When he injected mice with embryonic stem cells genetically identical to the mice's own tissues, the new cells thrived, growing into a large clump of adult tissues.

All of the mice produced normal amounts of SOX2 during development, when the transcription factor plays a critical role in the genesis of embryonic and neural stem cells.

Mitchell and her colleagues eliminated this possibility when they deleted these nearby regions in the genome of mice and found there was no impact on the gene's ability to be turned on in embryonic stem cells.

These are images of mouse embryonic stem cells which grow in a round colony of cells (A) and express Sox2 (B), shown in red.

«We studied how the Sox2 gene is turned on in mice, and found the region of the genome that is needed to turn the gene on in embryonic stem cells,» said Professor Jennifer Mitchell of U of T's Department of Cell and Systems Biology, lead invesigator of a study published in the December 15 issue of Genes & Development.

The group inserted an algal gene that codes for a light - responsive protein into mouse embryonic stem cells.

Niakan and colleagues predicted from earlier work with mice and human embryonic stem cells that the protein OCT4 would be necessary for the epiblast cells to develop correctly.

McKay announced that he had mitigated the symptoms of Parkinson's in rats by using mouse embryonic stem cells that he had turned into dopamine - producing brain cells.

Embryonic stem (ES) cells, harvested from three - and - a-half-day-old mouse embryos or five - and - a-half-day-old human embryos, are referred to as pluripotent because they can become any of the thousands of cell types in the body.

Researchers from the University of California, Berkeley, have found a way to reprogram mouse embryonic stem cells so that they exhibit developmental characteristics resembling those of fertilized eggs, or zygotes.

Smith and Martello plan to encourage mouse embryonic stem cells to turn into neurons, using Microsoft's formal analysis tools as a guide.

The scientists already knew how to encourage mouse embryonic stem cells to express nestin, and they wondered if they could coax their nestin - positive cells to take on more characteristics of pancreas cells.

An ambitious plan to map the genome's regulatory elements will focus first on mouse embryonic stem cells.

Still, the genetic homogeneity of largely inbred mouse strains may be misleading when it comes to understanding human stem cells, cautions Peter Andrews, professor of biomedical science and co-director of the Centre for Stem Cell Biology at the University of Sheffield, U.K. «In the human, every embryonic stem cell that we're working with that comes from a different person is genetically different,» says Andrstem cells, cautions Peter Andrews, professor of biomedical science and co-director of the Centre for Stem Cell Biology at the University of Sheffield, U.K. «In the human, every embryonic stem cell that we're working with that comes from a different person is genetically different,» says AndrStem Cell Biology at the University of Sheffield, U.K. «In the human, every embryonic stem cell that we're working with that comes from a different person is genetically different,» says Andrstem cell that we're working with that comes from a different person is genetically different,» says Andrews.

There is promising news today for those who hope to turn the potential of undifferentiated stem cells into medical miracles: Researchers are reporting a way to produce insulin - producing cells from mouse embryonic stem cells.

Studying mouse embryonic stem cells, they removed Grb2, a protein essential to the ability of the stem cell to transform into other cell types, from the cells.

Now, a new paper suggests that mouse embryonic stem cells can indeed accomplish this feat and lead to a partial recovery for animals with brain damage akin to Parkinson's.

They have learned how to turn on and off essential genes and how to transform embryonic stem cells into retinal cells, which can be transplanted into mice to restore vision.

The team injected about 2000 mouse embryonic stem cells each into the brains of 25 rats who had previously had their dopamine - producing neurons damaged, which causes a characteristic tendency to move in circles.

Mouse embryonic stem cells were turned into something resembling spermatids, the round cells that mature into sperm, by Jiahao Sha of Nanjing Medical University in China and his team.