Mouse
embryonic skin tissue.
Not exact matches
Scientists looking for new methods to make human
tissue have successfully used cloning technology to create
embryonic stem cells from
skin cells.
Organlike
tissue bits can be generated from pluripotent stem cells that are either plucked from embryos or created by taking a person's adult
skin or blood cells and chemically inducing them to revert to an
embryonic - like state.
Pluripotent stem cells include
embryonic stem cells, which are derived from early embryos, and induced pluripotent stem cells, which are made by reprogramming cells taken from adult
tissues such as
skin.
After analysing the presence of NANOG in different mouse
tissues by immunohistochemistry, the CNIO team demonstrated that, in addition to being present in
embryonic tissue, this factor is also found in stratified epithelia such as the esophagus,
skin or vagina.
A group that included researchers at the Wellcome Trust Sanger Institute and the University of Cambridge, both in the United Kingdom, developed a possible treatment for A1ATD by first reprogramming a
skin cell from a patient into iPS cells, which are
embryonic - like cells that can develop into many
tissue types.
Both teams successfully used these to reprogramme
skin cells in a lab dish into cells resembling
embryonic stem cells, which have the ability to turn into any
tissue of the human body.
The research used
skin samples from five men to create what are known as induced pluripotent stem cells, which closely resemble
embryonic stem cells in their ability to become nearly any
tissue in the body.
The potential of iPS cells to help treat everything from damaged heart
tissue to Parkinson's disease, has prompted intensive research that has looked into the use of
skin fibroblast cells as an alternative to controversial
embryonic stem cells.
They successfully converted mature mouse
skin cells into what they called induced pluripotent stem (iPS) cells that had the same wide - open potential as
embryonic stem cells — which the researchers showed by turning their iPS cells into nerve and connective
tissue cells.
There are studies on
embryonic stem cells, which can make all the
tissues of your body, and people over the past couple years have been able to take a set of genes and put them in and reprogram the
skin cells to think they're an
embryonic cell and therefore being able to make all the
tissues of your body.
InvivoSciences makes engineered heart
tissues from mouse
embryonic stem cells and stem cells from differentiated adult
tissues in humans, such as fat and
skin.
Six
tissue types, they found, were significantly «undertargeted» by pharmaceutical research: male reproductive
tissues,
embryonic structures,
skin, cartilage, bone and lymph.
Some researchers are using induced pluripotent stem (iPS) cells —
tissue - specific cells (usually
skin cells, but sometimes other
tissue cells) that are reprogrammed in the lab to behave like
embryonic stem cells — to grow rods and cones or RPE cells.
Dr. ZON: Well, it turns out that when you're making these
tissues, and we make many of these cells,
skin cells, that are reprogrammed to think that they're
embryonic cells, we make many of them here at Children's, they have a certain propensity to differentiate.