Not exact matches
From the
embryonic stem cells, the researchers produced a
type of
tissue called retinal pigment epithelium (RPE).
Embryonic stem cells are pluripotent, able to create all cell types, save more embryoni
Embryonic stem cells are pluripotent, able to create all cell
types, save more
embryonicembryonic tissue.
The newly discovered human cells, named «cord - blood - derived
embryonic - like stem cells» or CBEs, are not quite as primitive as
embryonic stem cells, which can give rise to any
tissue type of the body.
ERRORS have occurred in a
type of stem cell that could be used instead of
embryonic stem cells — and in
tissues made from them.
All stem cells are immature cells known for their ability to multiply indefinitely and give rise to progenitor cells that mature into specific cell
types that populate the body's
tissues during
embryonic development.
Since
embryonic stem cells can differentiate into any
type of
tissue, they have the potential to treat an almost unending array of medical conditions — replacing damaged or lost body parts or
tissues, slowing degenerative diseases, even growing new organs.
The results help fill in the scientific puzzle kicked off by Dolly's cloning, which proved that mammalian egg cells were capable of dissolving the genetic roadblocks that limit the potential of most adult cells to give rise to only a single
type of
tissue — that of the organ from which they hail — whereas
embryonic stem cells have the potential to become virtually any kind of body
tissue.
In contrast to
embryonic stem cells, when adult stem cells divide, their offspring are only able to develop at the same site and in certain
tissue types.
«
Embryonic stem cells are pluripotent, meaning they have the ability to become any
type of
tissue,» Fuchs says.
But even more far - ranging treatments may be possible with
embryonic stem cells, the blank - slate cells that give rise to all organs and
tissue types and that (theoretically) can repair all forms of organic damage and disease.
There is evidence that chronic disabilities such as spinal cord lesions, diabetes, and Parkinson?s disease, where replacement of just one cell
type restores
tissue function, can be treated with differentiated
embryonic stem cells.
By contrast, most
embryonic and induced pluripotent stem cells are more restricted in their developmental potential, able to form
embryonic cell
types, but not extra-
embryonic tissues.
Several years ago, one of the students in Verma's lab noticed that BRCA1 is very active in the neuroectoderm, a sliver of
embryonic tissue containing neural stem cells that divide and differentiate into the brain's vast assortment of cell
types and structures.
A group that included researchers at the Wellcome Trust Sanger Institute and the University of Cambridge, both in the United Kingdom, developed a possible treatment for A1ATD by first reprogramming a skin cell from a patient into iPS cells, which are
embryonic - like cells that can develop into many
tissue types.
In this edition, we're going to take a look at a very interesting tool that can be used for creating (excuse the pun) specific, targeted DNA modifications in transgenic animals,
embryonic stem cells, and / or
tissue - specific cell
types: Cre - lox recombination.
Unlike
embryonic stem cells, which are developmental blank slates that can generate virtually all
types of cells found in adult humans, adult stem cells are thought to possess limited potential to transform into cells found in their
tissues of origin.
Six
tissue types, they found, were significantly «undertargeted» by pharmaceutical research: male reproductive
tissues,
embryonic structures, skin, cartilage, bone and lymph.
By combining the use of magnetic tweezers with in vivo laser ablation, we locally control physiologically relevant deformations in wild -
type Drosophila
embryonic tissues.
Adult stem cells were once believed to be more limited than
embryonic stem cells, only giving rise to the same
type of
tissue from which they originated.
And in a similar way you have heart
tissue that's
embryonic, fetal and adult, and we don't really know which
type of
tissue is being developed, and that needs to be worked on more specifically.
The Society believes that research involving the transfer of a human nucleus into an animal egg will lead to important new knowledge about cell nuclear replacement (CNR) technology and, if it were to prove possible to produce
embryonic stem cells by this route, would increase understanding of how to programme these cells to develop into different
tissue types.
But it would allow so - called therapeutic cloning in which a patient's cells are coaxed to an
embryonic state where they regain the potential to create all of the body's different
tissue types.
Embryonic stem cells derived from human blastocysts have the key advantage of pluripotency, meaning that they form nearly all cell
types but also have the disadvantage of forming tumors in vivo, which may limit clinical application to
tissue engineering rather than cell transplantation.
Neural stem cells are found in adult or fetal brain and spinal cord or derived from
embryonic stem cells, which have the capacity to become any cell
type in the body, or induced pluripotent stem (iPS) cells,
tissue - specific cells that are reprogrammed in the lab to behave like
embryonic stem cells.
Embryonic stem cells — «pluripotent» cells that can develop into any
type of cell in the human body — hold tremendous promise for regenerative medicine, in which damaged organs and
tissues can be replaced or repaired.