Sentences with phrase «embryos using animal»

Not exact matches

By using engineered zinc - finger nucleases (ZFNs) designed to target an integrated reporter and two endogenous rat genes, Immunoglobulin M (IgM) and Rab38, we demonstrate that a single injection of DNA or messenger RNA encoding ZFNs into the one - cell rat embryo leads to a high frequency of animals carrying 25 to 100 % disruption at the target locus.

Using gene therapy to insert the gene, they expressed the synthetic gene in adult mice or in zebrafish embryos, and witnessed remote activation of neurons the presence of a magnetic field through the altered behavior of the animals.

But overall, the resulting toxicity of the wastewater due to its silver content was negligible to zebrafish embryos — a model animal used in toxicity studies.

Using her new culture system, she joined forces with colleagues to research which cells in an embryo contribute to which parts of the adult animal, a process called fate - mapping.

The tool has been used to make mutations or correct them in animals and in human cells, including human embryos (SN: 10/14/17, p. 8).

The group, led by Hwang Woo Suk at Seoul National University, cloned human embryos using somatic cell nuclear transfer, a process that biologists have used to clone live animals.

Using gene therapy to insert the gene, they expressed the synthetic gene in adult mice or in zebrafish embryos, and witnessed remote activation of neurons in the presence of a magnetic field through the altered behavior of the animals.

His recent published work describes the rescued visual function in animals using retinal pigment epithelial cells derived from human embryonic stem cells and a method for deriving stem cells using a single - cell approach that does not harm embryos.

Rieger used zebrafish larvae to model peripheral neuropathy because the embryos develop rapidly and because the larval fish are translucent, making them ideal for studying the progression of nerve degeneration in live animals.

Instead, NIH had seen «indications» that «scientists are considering exploring the use of human pluripotent cells in early stage animal embryos,» including to grow human tissues or organs.

The workshop is lead by Martin Fray and his team (MLC, MRC Harwell) 13th Transgenic Technology Meeting (TT2016) Mouse Cryopreservation Workshop 16th — 18th March 2016 (Wednesday — Friday) This 3day course is intended to give animal technologists hands - on experience of the murine embryo and spermatozoa freezing techniques routinely used at archiving nodes serving the European Mouse Mutant Archive (EMMA).

He has most recently used the knowledge of how a heart is built in an embryo to create beating heart muscle cells from connective tissue in adult animals, effectively regenerating healthy muscle cells from scar tissue after a heart attack.

A coalition of Britain's leading medical charities had earlier urged MPs to approve stem cell research using human - animal hybrid embryos.

In 2013, Peterson and his colleagues Joanna Yeh and Keith Joung were first to use the new technology to engineer a new strain of animal — a zebra - fish missing the GSK3ß gene, which encodes an enzyme involved in energy metabolism and the development of cell and body structures as an embryo grows.

She works in a WSU lab that focuses on evaluating hormonal regulation in the oviduct and uterus during fertilization, pre-implantation embryo development and embryo transport using genetically engineered animal models.