Their results, the researchers conclude, «show that computationally designed proteins have potent anti-viral efficacy in vivo and suggests promise for development of a new class of HA stem - targeted antivirals for both therapeutic and prophylactic protection against seasonal and
emerging strains of influenza.»
«We are dealing with
an emerging strain of this virus.
Not exact matches
For example, if we weight expected returns, it is nearly impossible to give any weight at all to a credit
strained environment and still justify a positive investment position, because
of the size
of the losses that can
emerge in credit -
strained conditions.
Last week was not a crash, though a free - fall appears increasingly possible, as the reality
of emerging recession (and all that it implies for fresh credit risks, sovereign defaults, fiscal imbalances, banking
strains and other problems) will likely smash against the consensus view
of economic expansion in next few months.
As the tarantellas and the polkas at last faded away, only the rising
strains of the Star Spangled Banner could be heard as all the immigrants
emerged from the melting pot
of Americanization.
With the right funding commitments in place, the Global Fund can help ensure that no child is born with HIV by 2015, that we end the public health threat
of malaria as we know it, and
emerging drug resistant
strains of TB are brought under control.»
But according to Cross» 1999 biography, he is an adherent
of Odinism, a neo-pagan religion that experts say has
emerged as one the most vicious
strains in the white supremacist movement.
«In the great formative period
of theistic philosophy, which ended with the rise
of Mahometanism, after a continuance coeval with civilization, three
strains of thought
emerge which, amid many variations in detail, respectively fashion God in the image
of an imperial ruler, God in the image
of a personification
of moral energy, God in the image
of an ultimate philosophical principle.»
Is missional a new, more mature
strain of the
emerging church movement?
Already there are signs
of the overuse
of antibiotics in animal husbandry resulting in antibiotic resistant
strains of bacteria
emerging.
Thorpe's dark side
emerged during a Feb. 2 game against the Phoenix Suns at The Palace
of Auburn Hills, when a sideline confrontation with Collins sparked a six - week stretch
of strained relations.
What does trouble me is BPI's use
of a raw material which by its very nature is highly pathogenic, such that we all might be endangered in the case
of human error (as when BPI's ammonia system stopped working for sixty seconds in 2009, leading to 26,000 + pounds
of infected meat)(http://nyti.ms/56MIYK) or a new
strain of E coli — not part
of BPI's admirably advanced testing protocol —
emerges (as one did in Germany last summer, killing 345 and sickening 3,700 +.)
For example, when Jones writes about the first multi-drug-resistant plasmid — a transmissible ring
of DNA —
emerging in a
strain of plague in Madagascar, he muddies the water with unclear uses
of «it».
Novel
strains of influenza
emerge periodically and can pose major challenges for health planners.
The study, «The efficacy
of the BCG vaccine against newly
emerging clinical
strains of Mycobacterium tuberculosis,» was published in the journal PLOS One in September.
In 1999, a lethal
strain of a related yeast, Cryptococcus neoformans,
emerged on Vancouver Island in British Columbia, Canada, through same - sex mating.
But this year, a new
strain of H2 flu
emerges in Russia and spreads around the world, killing about 1 million people.
The lethal Sin Nombre variant
of hantavirus had
emerged in the Southwestern United States years earlier, and tenOever wanted to compare the endemic local virus with that
strain.
Yoshihiro Kawaoka
of the University
of Wisconsin - Madison, lead researcher on the other study, adds that the meeting allowed him and Fouchier to explain their work, including the potential benefits for surveillance
of emerging flu
strains (Nature 481, 417 - 418; 2012) and for vaccine preparation (Nature 482, 142 - 143; 2012).
This one - two punch protected the test subjects against influenza A viruses that had
emerged in 1934 and 2007, and other experiments showed that the antibodies it generated successfully neutralized a wide variety
of flu
strains.
«We need a constellation
of genes, including those for
strain markers and toxins, that could be used to identify dangerous bacteria,» says Glenn Morris, director
of the
Emerging Pathogens Institute at the University
of Florida in Gainesville.
If the new combination
of gene variants make the offspring better suited for growth in its current environment, that bacterium will rapidly divide asexually, outcompete its parental (or sibling)
strains and become established as an
emerging strain or species in its own right.
Then the researchers looked at the way those
strains behaved in mice, ferrets and monkeys compared with two other types
of H7N9: a less infectious version that first
emerged in 2013 and the one isolated from the patient in 2016.
Despite being curable with multidrug therapy, leprosy still persists in many developing countries, with more than 200,000 new cases every year and increasing drug - resistant
strains of the leprosy bacterium, Mycobacterium leprae,
emerging.
As more mycobacterial genomes are sequenced, a picture is
emerging that Distributive Conjugal Transfer may have shuffled the genomes
of environmental mycobacteria to create a
strain that was particularly well suited for growth in mammalian lungs.
Professor Ajit Lalvani from the National Heart and Lung Institute at Imperial College London, who led the study, said: «New
strains of flu are continuously
emerging, some
of which are deadly, and so the Holy Grail is to create a universal vaccine that would be effective against all
strains of flu.»
Strains of S. pyogenes resistant to macrolide antibiotics have emerged, however all strains remain uniformly sensitive to peni
Strains of S. pyogenes resistant to macrolide antibiotics have
emerged, however all
strains remain uniformly sensitive to peni
strains remain uniformly sensitive to penicillin.
Evidence for this reconnaissance
emerged in 2009, when University
of California, Davis, plant pathologist Pamela Ronald discovered a bacterial protein called Ax21 in some
strains of rice.
So H1N1 in itself is a, you know, broad category
of viruses that circulate in humans, even now; they are not as fearsome as the original
strain when it first
emerged.
While the new discovery confirms scientists» ideas about the evolution
of disease, the worrying implication is that the same process could cause other virulent
strains of cholera to
emerge at any time.
He has long advocated global cooperation in the surveillance
of circulating flu viruses to spot
emerging new
strains so public health officials could plan a response and drug companies could get a head start in making vaccines.
Over the last decade,
strained nanomechanical oscillators have
emerged as an important paradigm owing to their anomalously high quality factors; however, this trend is not as much a design choice as an artifact
of large stresses naturally produced at the nanoscale.
Eppinger, a member
of the UTSA South Texas Center for
Emerging Infectious Diseases, calls the method he developed at UTSA a form
of whole genome sequence typing
of outbreak
strains.
Several highly virulent
strains of fungi have
emerged in recent years around the world, and the oomycete Phytophthora infestans remains a persistent problem even 168 years after causing the great Irish potato famine.
Though most do not think it likely that a nastier
strain will
emerge, many are worried that if it did, their local hospitals and other parts
of...
The findings, which appear in the March 11 issue
of Cell Host & Microbe, contradict previous reports from Indian health officials that the
strain has not changed from the version
of H1N1 that
emerged in 2009 and has been circulating around the world ever since.
In the face
of emerging drug - resistant HIV
strains, the find could offer a new approach
In just the past few years,
strains of Escherichia coli have
emerged that can thrive in salted foods like sausage or acidic foods such as apple juice, and certain
strains of Salmonella have developed the ability to resist food - processing temperatures that kill other organisms.
Skov adds: «I fear that if we don't get antibiotic use in livestock under control, then new, more virulent
strains of livestock - associated MRSA will
emerge that pose a much greater threat to human health than what we are currently facing.»
After hibernating in refrigeratorlike chambers containing the compound, which is produced by a soil bacterium (a
strain of Rhodococcus rhodochrous), diseased little brown and northern long - eared bats
emerged healthy.
A leader in the
emerging field
of synthetic biology, Amyris is well known for developing a
strain of yeast for large - scale manufacture
of a precursor to the antimalarial drug artemisinin, for which the Asian plant source is in short supply.
The threads collected data on tissue health (e.g. pressure, stress,
strain and temperature), pH and glucose levels that can be used to determine such things as how a wound is healing, whether infection is
emerging, or whether the body's chemistry is out
of balance.
Of the
emerging economies, China and India rank 120th and 177th respectively, reflecting the
strain population pressures and rapid economic growth impose on the environment, note the researchers.
A dramatic pattern
emerged for H3N2, the most virulent
of the three
strains that return each winter.
He now believes the AIDS epidemic may have
emerged not because humans acquired HIV from monkeys, but because existing human
strains of HIV mutated to become more infectious.
More recently,
strains of tuberculosis have
emerged that are resistant not only to front - line antibiotics, but also to one or more drugs within each
of the two most important classes
of second - line drugs — broad - spectrum antibiotics called fluoroquinolones, and injectable agents (amikacin, capreomycin and kanamycin).
The finding is exciting «because it suggests that the seasonal flu vaccine boosts antibody responses and may provide some measure
of protection against a new pandemic
strain that could
emerge from the avian population,» said senior study author Paul G. Thomas, PhD, an Associate Member in the Department
of Immunology at St. Jude.
Explosive growth in the world's
emerging economies has lit up patches
of the map that barely flickered a few decades ago, jacking up the demand for power and
straining known oil reserves to the limit.
Since the turn
of the century, however, aggressive new
strains have
emerged — such as «Ug99», first detected in Uganda in 1999 — that infect widely grown varieties
of wheat.
Every year,
strains of drug - resistant tuberculosis will
emerge that are more transmissible, more difficult to treat, and more widespread in the community.