Sentences with phrase «encoded cell surface»

Reduced expression of the Indy (= I'm Not Dead Yet) gene, which encodes a cell surface transporter for tri - and dicarboxylic acids, prolongs life and health span in a manner akin to caloric restriction in D. melanogaster and C. elegans.

Not exact matches

When similar analysis was performed on the db mice, it was found that the disrupted db gene was responsible for encoding a protein that functions as a leptin receptor: When it binds circulating leptin at the cell surface, it sets in motion a biochemical cascade inside the cell.

One key gene encodes the making of a receptor called TREM2, a docking site for molecules on the surface of microglia and other innate immune cells.

That gene encodes a sugar - studded protein on the virus's outer surface that helps the virus stick to and invade human cells.

How it hides: In a normal cell, genes encode instructions for surface proteins known as the major histocompatibility complex (MHC).

The tentacles are actually strands of DNA encoded to match an enzyme on the surface of leukaemia cells.

Without it, NFAT initiates a negative regulatory program that activates genes encoding inhibitory cell surfaces markers and blunts signals received by the T cell receptor.

At the heart of the pathway lies the daf - 2 gene, which encodes a member of the insulin family of cell surface receptors.

The isolation and nucleotide sequence of a cDNA encoding the T cell surface protein T4: a new member of the immunoglobulin gene family.

Upregulated genes clustered into at least 7 functional groups, including immediate early genes or transcription factors, cell - cycle related genes, stress - responsive protein genes, cell signaling protein genes, cell adhesion and cell surface protein genes, genes involved in translation and protein turnover, and genes encoding metabolic proteins.

The vaccines deliver mRNA encoding for hemagglutinin to the body's cells, directing them to produce and express this viral antigenic protein transiently on the cell's surface, much like a native infection would do, but without the ability to cause disease.

He isolated the genes encoding proteins that confer immunological identity to the two main types of cells in the human immune arsenal: the CD4 protein, which dots the surface of helper T cells, and the CD8 protein, which adorns killer T cells.

This type of «killer» T cell responds to previously encountered cell - surface molecules — including the fragments of SIV proteins encoded by the genes in the CMV / SIV vaccine — and destroys SIV - infected cells.

The Major Histocompatibility Complex (MHC) is a region of the genome in dogs that contains genes that encode a group of cell surface proteins known as Dog leukocyte antigens (DLA).