Sentences with phrase «encoding huntingtin»

HD is an autosomal dominantly inherited neurodegenerative disorder caused by a CAG repeat expansion in the gene encoding huntingtin.

HD is caused by an unstable expansion of CAG repeats in the gene encoding huntingtin protein.

Huntington's disease is an inherited genetic disorder caused by mutations in the gene that encodes huntingtin protein.

Not exact matches

The huntingtin gene encodes a large scaffold protein, with many interaction partners, which is thought to be involved in intracellular trafficking.

In humans, Huntington's is an inherited disease caused by a gene encoding a toxic protein, called mutant huntingtin, which causes brain cells to die.

Huntington's disease is caused by a gene encoding a toxic protein (mutant huntingtin) that causes brain cells to die.

In a nonhuman primate model geneticist Anthony Chan DVM, PhD, and his colleagues at Yerkes developed, rhesus macaques carry a gene encoding a fragment of mutant human huntingtin.

That means a healthy parent whose huntingtin gene encodes proteins with 35 repeats may produce a child with 36 repeats.

Huntington's disease is caused by a gene encoding a toxic protein (mutant huntingtin or mHTT).

These three monkeys carried a gene encoding a fragment of mutant human huntingtin.

Huntington's is an inherited disease caused by a gene encoding a toxic protein (mutant huntingtin) that causes brain cells to die.

Huntington's disease is caused by a gene encoding a toxic protein (mutant huntingtin or mHTT) that causes brain cells to die.

Huntington's disease (HD) is a progressive neurodegenerative disorder caused by a CAG: CTG repeat expansion in exon 1 of the gene that encodes the polyglutamine - containing protein Huntingtin.

Huntingtin null neurons exhibit a significant reduction in transcripts encoding proteins destined for the extracellular space, many of which are components of the extracellular matrix or involved in cellular adhesion, receptor binding and hormone activity.