It wasn't until 1992 that researchers discovered
endocannabinoids produced naturally in the body.
Cannabinoids in marijuana and
endocannabinoids produced in the body can support the body's immune system and therefore are attractive targets for the development of anti-inflammatory therapeutics, she said.
Not exact matches
The primary psychoactive compound in marijuana, tetrahydrocannabinol (THC), mimics the structure of molecules called
endocannabinoids that the human body
produces naturally.
Using mice, this study found that in obesity, CB1 cannabinoid receptors become enriched on the nerve terminals that normally inhibit orexin neuron activity, and the orexin neurons
produce more of the
endocannabinoids to activate these receptors.
In the 1990s, researchers realized humans can
produce their own cannabinoids through the body's
endocannabinoid system (ECS).
Current studies in the Parsons laboratory are investigating whether binge patterns of drug consumption evoke similar
endocannabinoid disruptions, and they are probing the influence of impaired
endocannabinoid signaling in the excessive motivational effects
produced by drug - associated conditioned cues.
He developed an innovative microdialysis approach that allows the in vivo sampling of lipid signaling molecules in the brain (including
endocannabinoids) and has demonstrated that voluntary self - administration of ethanol, heroin, and cocaine
produces distinct drug - and region - specific changes in brain
endocannabinoid levels.
More precisely, the
endocannabinoid system is a group of specialized lipids, their receptors and the enzymes that
produce and degrade them.
The brain's
endocannabinoid system may also help
produce runner's high, reports an unrelated German study published last month.
The
endocannabinoid system
produces a number of chemicals that bind to the CB1, CB2 and minor receptors.
The phytocannabinoids
produced by cannabis are not the same thing as the
endocannabinoids, but the similarities are what make it so vitally important as a medicine.