Acute and chronic
endocrine effects of noise: Review of the research conducted at the Institute for Water, Soil and Air Hygiene Ising, H.; and Braun, C.
As EDSTAC worked to develop a scientific screening program to guide regulatory decisions on
the endocrine effects of chemicals, the US government released its first requests for applications for EDC research.
Frederick vom Saal publishes a study alleging
endocrine effects of BPA at very low doses, giving rise to the still - unproven hypothesis known as the «low - dose hypothesis.»
Tulane University publishes a paper alleging
endocrine effects of combined exposures to low levels of pesticides.
Nordeen and colleagues show that luteolin blocks some of
the endocrine effects of the hormone progesterone.
Not exact matches
For instance, the researchers didn't look at other contaminants, like the
effects of endocrine disruptors, flame retardants and pesticides on human health and early deaths.
Phenol - based products are proven
endocrine disruptors with a host
of well - studied deleterious health
effects
>> Read the complete research study:
Endocrine disrupting chemicals and other substances
of concern in food contact materials: An updated review
of exposure,
effect and risk assessment in the Journal
of Steroid Biochemistry and Molecular Biology.
Adversity, especially in early childhood, has a powerful
effect on the development
of the intricate stress - response network within each
of us that links together the brain, the immune system, and the
endocrine system (the glands that produce and release stress hormones, including cortisol).
She was immediately attracted to the mysteries
of toxic plastics and their
effect on children and quickly learned that avoiding
endocrine - disrupting chemical in common household products can be overwhelming.
The evidence for epigenetic
effects on emotion regulation is quite solid: Early caregiving experiences can affect the expression
of the genes that regulate a baby's stress and they can shape how the
endocrine system will mobilize to stress.
In light
of Father's Day, I wanted to share some information on the harmful
effects that could be caused by
endocrine disrupting chemicals, or EDCs, and how exposure could be negatively affecting the men in our lives.
Endocrine and clinical
effects of myo - inositol administration in policystyc ovary syndrome.
Vom Saal has spent several decades researching the potent
effects of everyday low - dose exposure to chemicals like bisphenol A (BPA) that are known as
endocrine disrupters.
However, other research has suggested that the estrogen - like
effects of isoflavones may reduce the effectiveness
of endocrine therapies used to treat breast cancer.
«However, based on our results, we do not see a detrimental
effect of soy intake among women who were treated with
endocrine therapy, which has been hypothesized to be a concern.
The report, which drew heavily on two Environmental Protection Agency (EPA) workshops held in 1995, also recommends more research on such topics as DNA biomarkers that can gauge an organism's exposure to
endocrine disruptors; models for predicting how
endocrine disruptors are metabolized; mechanisms
of how
endocrine disruptors act at a cellular level; and the
effects of mixtures.
Among areas the panel says should be studied further are possible cancer, reproductive, neurological, and immunological
effects of endocrine disruptors.
The researchers studied the
effect of di -(2 - ethylhexyl) phthalate (DEHP), which is among the most widely used
endocrine - disrupting chemicals.
While changes in insulin secretion are unlikely to play a major role in the acute
effects of SD, cellular stress in pancreatic tissue suggests that chronic SD may contribute to the loss or dysfunction
of endocrine cells, and that these
effects may be exacerbated by normal aging, say the researchers.
To further probe the links between the
endocrine system and aging, he focused on the
effects of hormones upon the brain.
Some chemical issues that Geoff?s team deals with have a high - profile, like
endocrine - disrupting substances; many chemicals, both natural and man - made, are known to adversely
effect the hormone systems
of humans and animals, and there is growing concern about the link between the presence
of these substances in their environment and their harm to wildlife.
Indeed, concentrations
of known
endocrine disrupters in rivers often seem to be too low to explain harmful
effects in aquatic wildlife, says Kolodziej.
Although there remain some
effects of treatment on hearing,
endocrine, and neurocognitive outcomes — particularly in younger patients — other late
effects common in photon - treated patients, such as cardiac, pulmonary, and gastrointestinal toxic
effects, were absent.»
However, it is not known whether a mother's alcohol use before conception also could have negative
effects on her child's health and disease susceptibility during adulthood,» said principal investigator Dipak Sarkar, Ph.D., DPhil, a distinguished professor at Rutgers University in New Brunswick, N.J., and director
of its
endocrine research program.
The
endocrine disrupting
effects of chemicals have generally not been adequately studied.
The
effects of endocrine - disrupting chemicals may be particularly insidious in people who smoke, Zoeller said.
Dr. Adibi is looking ahead to future studies where she will enroll women in the earliest stages
of pregnancy at clinics in Pittsburgh to assess exposures to
endocrine disruptors and measure
effects on the placenta and the baby.
Risk
of overlooking harmful
effects of chemicals A reason why detection
of early reproductive aging is important is that most studies
of endocrine disrupting
effects end before the experimental animals are a year old.
The toxicological
effects of these so - called
endocrine disrupters on the reproductive system have so far been tested more thoroughly in boys than in girls.
«For the first time, we have shown a direct link between exposure to
endocrine disrupting chemicals from industrial products and adverse
effects on human sperm function,» said Niels E. Skakkebaek, professor and leader
of the Danish team.
Proving the deleterious
effects of endocrine disruptors on human beings has been difficult due to a lack
of suitable experimental systems.
«Our work highlights the fact that we need to test the
effects of potential
endocrine disrupting chemicals in both rat and human cells to be able to accurately predict the risk,» said Professor Habert.
It is especially important to take account
of cocktail
effects because people are exposed to many types
of endocrine disruptors at the same time over the course
of a normal day,» Julie Boberg explains.
The
effects of morphine, naloxone, and kopioid manipulation on
endocrine functioning and social behavior in monogamous titi monkeys (Callicebus cupreus).
There are lots
of endocrine active substances, but the number
of substances that also produce adverse
effects — «
endocrine disruptors» — is much smaller.
The launch
of the
Endocrine Disruptor Screening Program (EDSP) in the late 1990s marked a new direction for how EPA would review certain chemicals for endocrine activity and
Endocrine Disruptor Screening Program (EDSP) in the late 1990s marked a new direction for how EPA would review certain chemicals for
endocrine activity and
endocrine activity and
effects.
EPA has used standardized test methods since the early 1970s to detect potential adverse
effects of chemicals, including
endocrine disruptive
effects.
Systemic enamel pathologies may be due to anti-androgenic
effects of some
endocrine disruptors.
We attribute this to the immediate proximal
effect of the food promoting neural and
endocrine signalling [39]--[41].
The projects concern the
effects of environmental exposures such as
endocrine disrupting chemicals, flame retardants, pesticides, metals, particulate air pollution, as well as drugs, psycho - social stressors and ethnical disparities.
As more information about
endocrine disruptor
effects and mechanisms becomes available, it will be increasingly important to carefully quantify the extent
of human exposure to EDCs and assess the inherent risk in that exposure.
Scientific evidence now shows that some chemicals, especially
endocrine disrupting compounds, can exert negative
effects at extremely low levels
of exposure, sometimes with more serious or different
effects than at higher doses.
Effect of creatine and beta - alanine supplementation on performance and
endocrine responses in strength / power athletes.
day 1
of #caffeinefreeweek, and i'm sippin» on a dandy root coconut latte sprinkled with vietnamese organic cinnamon ☕️ that FOAM though this drank is packed to the brim with adaptogens and brain - boosting fats to give you a boost without the
endocrine disrupting
effects of caffeine.
Performance enhancing type drugs can cover these deficiencies up short term — but when these athletes don't have the muscle building, protein sparing
effects of these drugs, and their
endocrine systems have received no support from their diet... look out.
There are a few recommendations for those who are still in a dilemma whether they you should start a steroid cycle or want to experience rapid muscle gains, but are afraid
of the deleterious
effects steroids can have on the
endocrine system.
Even with the change to soy protein isolate, FDA bureaucrats engaged in the «rigorous approval process» were forced to deal nimbly with concerns about mineral blocking
effects, enzyme inhibitors, goitrogenicity,
endocrine disruption, reproductive problems and increased allergic reactions from consumption
of soy products.31 One
of the strongest letters
of protest came from Dr. Dan Sheehan and Dr. Daniel Doerge, government researchers at the National Center for Toxicological Research.32 Their pleas for warning labels were dismissed as unwarranted.
Elbek criticized the panel for rushing through the evidence
of soy genistein's phyto - toxicity and for largely disregarding damaging
effects caused by daidzein (metabolite equol) and glycitein, individually or in combination with other estrogenic
endocrine disruptors.
Examples include the Strom study (funded by the Infant Formula Council) that declared soy formulas «safe» in a great media blast but did not look at thyroid problems or asthma and whose data actually indicated reproductive problems; or the Klein literature study (carried out at a DuPont Children's Hospital; DuPont owns Protein Technologies, a manufacturer
of soy protein isolate) which declared that there is no evidence in the literature
of endocrine effects.