Sentences with phrase «endocytic pathway»
The "endocytic pathway" refers to a process in cells where substances are taken in from the outer environment and transported within the cell for various purposes. It is like a highway system for molecules, allowing cells to internalize and break down substances or to transport them to where they are needed. Full definition
Quantum dot - loaded monofunctionalized DNA Icosahedra for single particle tracking of endocytic pathways Nature Nanotechnology (2016) Dhiraj Bhatia, Senthil Arumugam, Michel Nasilowski, Himanshu Joshi, Christian Wunder, Valerie Chambon, Ved Prakash, Chloé Grazon, Brice Nadal, Prabal K. Maiti, Ludger Johannes, Benoit Dubertret, Yamuna Krishnan
science.institut-curie.org
The researchers used three endocytic pathways as markers to sort out 29 non-small cell lung cancer (NSCLC) lines into two distinct clusters characterized by their endocytic dysfunction.
The work, led by Assistant Professor Wu Min, showed how a major endocytic pathway mediated by the protein clathrin, was found to commence with periodic traveling waves of clathrin, which were coupled temporally and spatially to downstream cortical actin waves.
In HeLa cells, Shiga toxin B - subunit is transported from the plasma membrane to the endoplasmic reticulum, via early endosomes and the Golgi apparatus, circumventing the late endocytic pathway.
Finally, we position this hypothesis within the global context of endocytic pathway proposals that have emerged in recent years.
Numb is also a known regulator of Notch, a protein implicated in stem cell maintenance, and together, these observations have driven the development of new stem cell research projects, ranging from transcriptional profiling analysis of normal and cancer stem cells, to the in - depth characterisation of a number of critical signalling / endocytic pathways involving Numb / Notch / p53 (2, 3).
Therefore, we are investigating the involvement of the Numb / Notch / p53 interaction and endocytic pathways in stem cell self - renewal.
Bhatia # D, Arumugam # S, Nasilowski M, Joshi H, Wunder # C, Chambon # V, Prakash V, Grazon C, Nadal B, Maiti P, Johannes * L, Dubertret * B, Krishnan * Y (2016) Quantum dot - loaded monofunctionalized DNA Icosahedra for single particle tracking of endocytic pathways.
Major histocompatibility complex class II (MHC II) molecules capture peptides within the endocytic pathway to generate T cell receptor (TCR) ligands.
Transport and sorting of proteins and lipids along the endocytic pathway to the lysosome - like vacuole relies on a process called endosomal maturation, where early endosomes change surface composition and morphology before finally fusing with the vacuole.
Human iPSC models of neuronal ceroid lipofuscinosis capture distinct effects of TPP1 and CLN3 mutations on the endocytic pathway.
Carsten Schnatwinkel (Zerial, MPG)-- «Characterization of novel Rab5 effector proteins in the endocytic pathway» (2004)
They are present in apoptotic bodies of infected cells or can be exposed upon degradation of the microbes within the endocytic pathway.
Current projects are designed to obtain a complete molecular characterisation of these endocytic pathways.