Sentences with phrase «endocytic pathways»
Therefore, we are investigating the involvement of the Numb / Notch / p53 interaction and endocytic pathways in stem cell self - renewal.
http://www.ifom-ieo-campus.it/
Current projects are designed to obtain a complete molecular characterisation of these endocytic pathways.
Cholera toxin toxicity does not require functional Arf6 - and dynamin - dependent endocytic pathways.
Major histocompatibility complex class II (MHC II) molecules capture peptides within the endocytic pathway to generate T cell receptor (TCR) ligands.
The work, led by Assistant Professor Wu Min, showed how a major endocytic pathway mediated by the protein clathrin, was found to commence with periodic traveling waves of clathrin, which were coupled temporally and spatially to downstream cortical actin waves.
Human iPSC models of neuronal ceroid lipofuscinosis capture distinct effects of TPP1 and CLN3 mutations on the endocytic pathway.
Existence of a novel clathrin - independent endocytic pathway in yeast that depends on Rho1 and formin.
Role of the endocytic pathway in the counteraction of BST - 2 by human lentiviral pathogens.
Not exact matches
However, approximately 40 % of human (and most eukaryotic) proteins localize to chemically distinct subcellular environments, including the organelles that compose the secretory pathway, endocytic vesicles, mitochondria, lysosomes or they are secreted into the extracellular milieu.
Thus, our study shows that membrane exchange between the early endocytic and the biosynthetic / secretory pathways involves specific components of the Rab and SNARE machinery, and suggests that retrograde transport between early / recycling endosomes and the endoplasmic reticulum is critically dependent on the sequential action of two members of the Rab6 subfamily.
Therefore it is critical that nucleic acid - sensing TLRs bind their ligands and signal from the endocytic / phagocytic pathway.
Both Notch and p53 signalling are implicated in stem cell self - renewal (18, 19), and the endocytic protein Numb is connected to both these signalling pathways.