Sentences with phrase «endocytosis by»

Title: Control of Notch ligand endocytosis by ligand - receptor interaction Authors: Hansson EM, Lanner F, Das D, Mutvei A, Marklund U, Ericson J, Farnebo F, Stumm G, Stenmark H, Andersson ER, Lendahl U Date: 2010 Sep 1 Publication Details: J Cell Sci.

Negative regulation of dopamine transporter endocytosis by membrane - proximal N - terminal residues.

Clathrin light chain directs endocytosis by influencing the binding of the yeast Hip1R homologue, Sla2, to F - actin.

Endocytosis by random initiation and stabilization of clathrin - coated pits.

Not exact matches

After secretion, apolipoprotein E and cholesterol associate with high - density lipoprotein to form a particle that can deliver cholesterol to the liver by receptor - mediated endocytosis.

Endocytosis of Frizzled 4 (Fz4) in human embryonic kidney 293 cells was dependent on added Wnt5A protein and was accomplished by the multifunctional adaptor protein β - arrestin 2 (βarr2), which was recruited to Fz4 by binding to phosphorylated Dvl2.

Endosomes are machinery that tumor cells, via a process called endocytosis, can use to incorporate components into their environment and obtain energy by degrading them via autodigestion or autophagy.

But by hierarchical clustering of observed alterations in endocytosis, the researchers identified two distinct cancer phenotype clusters, one marked by mutations in the oncogene KRAS in mesenchymal cells and the other by changes in epithelial cells.

«Non-small cell lung cancers can be sorted in clusters by endocytic changes: Sorting cancer by defective endocytosis genes.»

They did it by using a chemical rapamycin which diffuses in to the cell allowing them to trigger endocytosis to occur all over the cell.

A cell can change the amount of these cell surface proteins by internalizing small portions of the membrane through endocytosis.

Endocytosis is not normal in cancer cells but how dysregulated the process is in cancer cells has just been revealed by Sarah Elkin and colleagues in the University of Texas (UT) Southwestern Medical Center lab of Sandra Schmid.

Endocytosis is a fundamental membrane trafficking process by which cells uptake external factors such as proteins and pathogens.

Complex cells like amoebae (pictured right) and white blood cells can «swallow» large particles by engulfing them and pinching off the «bubble» containing the particle, a process called endocytosis.

A deeper look into the mechanism by which alpha - synuclein inhibits endocytosis revealed toxic effects of the over-assembly of microtubules.

We know the initial target and the mechanism... [But] in order to step into [the treatment] stage, we should probably work a little bit more to know by what mechanism the microtubules interfere with endocytosis.»

For example, induced endocytosis can be shown to be an optimal solution for transmitting high - fidelity information by signaling receptors.

Clathrin - mediated endocytosis in snake motor terminals is directly facilitated by intracellular Ca2 +.

Exosome Uptake Depends on ERK1 / 2 - Heat Shock Protein 27 Signaling and Lipid Raft - mediated Endocytosis Negatively Regulated by Caveolin - 1.

Methods: Researchers Harish Shankaran, Haluk Resat and Wiley paired a new module - based systems theory approach with quantitative metrics for network function to show that receptor / ligand properties such as endocytosis can be described by just a few control parameters.

Visualization of Rab5 activity in living cells by FRET microscopy and influence of plasma - membrane - targeted Rab5 on clathrin - dependent endocytosis.

Targeting, Endocytosis, and Lysosomal Delivery of Active Enzymes to Model Human Neurons by ICAM -1-Targeted Nanocarriers.

Uptake of rabies virus into epithelial cells by clathrin - mediated endocytosis depends upon actin.

We have been studying endocytosis in a broader, systems perspective, by combining quantitative imaging, genome - wide RNAi screens with systems biology analysis.

Endocytosis is not required for the selective lipid uptake mediated by murine SR - BI.

Sphingosine 1 - phosphate - induced motility and endocytosis of dendritic cells is regulated by SWAP - 70 through RhoA.

Endocytosis of Ligand - Activated Sphingosine 1 - Phosphate Receptor 1 Mediated by the Clathrin - Pathway.

«Increased inward plasma membrane bending by ATP10A expression enhances endocytosis,» explains Hye - Won Shin of Kyoto University's Graduate School of Pharmaceutical Sciences.

Endosomes are the main organelles for sorting material that has been taken up from the exterior of the cell by the plasma membrane (endocytosis).

Recently, he has been focusing on the regulation of a family of yeast purine - cytosine permeases, including the transcriptional controls over their expression, and how, after these proteins bind to their cargo, they are targeted by the ubiquitin system for endocytosis and delivery to the vacuole.

Endocytosis provides the selective formation of big NP clusters only in diagnosis - specific cells, while fewer NPs incidentally accumulated by non-specific cells are insufficient to form an NP cluster.