Sentences with phrase «endogenous cell processes»
After editing occurs, the Cas9 - sgRNA RNP complex is degraded over time by endogenous cell processes, leaving no remaining footprint that would be capable of producing off - target effects.
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Our ancestors evolved to deal with these exobiotic toxins with robust endogenous antioxidant and detoxification responses, and in their absence (eg, in a highly processed diet), our cells don't get the expected cues to ramp up defenses.