Sentences with phrase «endogenous levels produces»

Reduction of htt to 50 % endogenous levels produces viable mice with no overt phenotypes (Duyao et al., 1995; Zeitlin et al., 1995) however more detailed evaluation has revealed deficits in cognition and motor behavior (Nasir et al., 1995) raising the possibility that lowered htt starting in development may have adverse effects in the mouse.

Not exact matches

A study by Dallas et al indicated that milk produced by women who deliver preterm demonstrates a high level of protein breakdown by endogenous proteases, with the investigators suggesting that such breakdown may reduce difficulties associated with the immature digestive systems of preterm infants.

Lead author X. Charlie Dong, Ph.D., associate professor of biochemistry and molecular biology at the IU School of Medicine, and colleagues monitored blood glucose levels and liver insulin sensitivity in mice with the endogenous Sestrin 3 protein and mice genetically engineered to not produce the protein.

This suggests that the instantaneous peak power delivered to the specimen may be an even more important metric of cell health than the total photon dose and should enable extended 3D observation of endogenous levels of even sparsely expressed proteins produced by genome editing.

This metabolism, or break down of testosterone, occurs in the same manner for both exogenous and endogenous testosterone (naturally produced testosterone), but because of an increased abundance of testosterone this may lead to higher than normal levels of these metabolites.