Sentences with phrase «endogenous ligands»
The phrase "endogenous ligands" refers to specific molecules that are naturally produced within the body and have the ability to bind to and activate certain receptors in the body. These ligands play important roles in various physiological processes and signaling pathways. Full definition
Subsequently, he established carbon monoxide as another gaseous transmitter and D - serine as a glial derived endogenous ligand of glutamate - NMDA receptors.
warrenalpert.org
We found that a prototypical autoreactive TCR bound CD1a when it was presenting a series of permissive endogenous ligands, while other lipid ligands were nonpermissive to TCR binding.
Among them, the most useful was demonstrated to be the Growth Hormone Releasing Peptide - 6 (GHRP - 6), before the discovery of the endogenous ligand ghrelin.
Although Nurr1 is a ligand - independent nuclear receptor, Dr. Kim hypothesizes that Nurr1 may have endogenous ligand (s) and is pursuing to identify and characterize potential Nurr1's endogenous ligand (s).
Our genetic approach in Drosophila melanogaster provides the first evidence, to our knowledge, that bombesin receptor signaling with its endogenous ligand promotes insulin production.
Our vigorous genetic approach combined with direct observations of Dilp production in IPCs provides the first evidence, to our knowledge, that Bombesin - related receptor signaling activated by its endogenous ligand promotes insulin production.
Bach1 has an endogenous ligand, heme, that inhibits Bach1 binding to ARE, thus allowing Nrf2 - mediated gene expression including that of heme - oxygenase - 1 (HMOX1), a well described target of Bach1 repression.
«Food for thought: an endogenous ligand of Rev - erb is heme (the iron - binding element in red blood cells).