They unearthed genomic fossils for so - called
endogenous retroviruses in highly diverse hosts, such as ray - finned fish and amphibians that had no previous link to retroviruses.
Inactivation of porcine
endogenous retrovirus in pigs using CRISPR - Cas9.
Not exact matches
Vestigial features, study of ebryonic development, biogeography, DNA sequencing, examining pseudogenes, study of
endogenous retroviruses, labratory direct examination of natural selection
in action
in E-Coli bacteria, lactose intolerance
in humans, the peppered moth's colour change
in reaction to industrial pollution, radiotrophic fungi at Chernobyl all add to the modern evolutionary synthesis.
Perhaps the most significant distinction between evolution and ID / creationism is evolution's ability to explain poor design features, e.g. male nip - ples, the recurrent laryngeal nerve, the presence / location of
endogenous retroviruses, and (one of my personal favorites) the presence of a defunct gene for egg yolk protein
in our placental mammal genomes.
Tangible proof can be found by studying vestigial features, ebryonic development, biogeography, DNA sequencing, pseudogenes,
endogenous retroviruses, labratory direct examination of natural selection
in action
in E-Coli bacteria, lactose intolerance
in humans, the peppered moth's colour change
in reaction to industrial pollution, radiotrophic fungi at Chernobyl... all of these things add to the modern evolutionary synthesis.
Other indications of evolution are too numerous to actually list
in full, but a few might be the clear genetic distinction between Neanderthals and modern man; the overlapping features of hominid and pre-hominid fossil forms; the progressive order of the fossil record (that is, first fish, then amphibians, then reptiles, then mammals, then birds; contradicting the Genesis order and all flood models); the phylogenetic relationships between extant and extinct species (including distributions of parasitic genetic elements like
Endogenous Retroviruses); the real time observations of speciation
in the lab and
in the wild; the real time observations of novel functionality
in the lab and wild (both genetic, Lenski's E. coli, and organsimal, the Pod Mrcaru lizards); the observation of convergent evolution defeating arguments of common component creationism (new world v. old world vultures for instance); and... well... I guess you get the picture.
Evolutionary theory has been validated
in the successful prediction of a wide range of biological observations, e.g., the fused 2nd human chromosome, the phylogenetic distribution of
endogenous retroviruses, the relative positions and features of intermediate and transitional fossils, etc, etc..
Removing the viruses — called porcine
endogenous retroviruses, or PERVs — creates piglets that can't pass the viruses on to transplant recipients, geneticist Luhan Yang and colleagues report online August 10
in Science.
Now a team led by Robin Weiss of London's Institute of Cancer Research reports that the «PK» porcine
endogenous retrovirus, which does not appear to harm pigs, can replicate
in mink and human cells.
To do so, the placenta may deploy a mercenary army of
endogenous retroviruses — viral genes embedded
in the mammal's DNA.
Vampire bat (Desmodus rotundus) samples from Mexico and from the Berlin Zoological Garden revealed a new
endogenous retrovirus (named DrERV after Desmodus rotundus
endogenous retrovirus) that is also present
in rodents and primates but is absent
in other closely related bat species.
The virus, called human
endogenous retrovirus W (HERV - W), codes for a protein that, when activated, sets off an inflammatory cascade
in the brain that leads to symptoms.
And
in lab experiments, these porcine
endogenous retroviruses (PERVs) tended to leap from pig to human cells.
Once
in a while,
retroviruses infect sperm and egg cells and become «
endogenous,» meaning they are passed down from generation to generation.
Sabunciyan has found that an unexpectedly large amount of the RNA produced
in the brain — about 5 percent — comes from seemingly «junk» DNA, which includes
endogenous retroviruses.
Exosomes,
endogenous retroviruses and toll - like receptors: pregnancy recognition
in ewes.
We are conducting a systematic survey to monitor genome stability, including transcriptional activation of
endogenous retroviruses (ERVs)
in the human genome following iPS reprogramming and differentiation.
In the new study, a team led by Harvard University's George Church — one of the pioneers of the CRISPR technique — used gene editing to remove all the copies of porcine
endogenous retroviruses (or PERVs) from their pig cells» DNA.
In their lingering twilight, our
endogenous retroviruses can still be dangerous to our health.
Recently, prospects for xenotransplantation brightened when Harvard geneticist George Church demonstrated the removal of dozens of
endogenous retroviruses from the pig genome,
in a tour de force of the CRISPR / Cas9 gene editing technique.
Finally, a 2011 study from Paprotka, et al. provided strong evidence that XMRV is a 22Rv1 - derived laboratory contaminant originating from recombination of two mouse
endogenous retroviruses during serial passage of CWR22
in nude mice [38].
On the contrary, recent evidence indicates that XMRV is a contaminant originating from the recombination of two mouse
endogenous retroviruses during passaging of a prostate tumor xenograft (CWR22)
in mice, generating laboratory - derived cell lines that are XMRV - infected.
In 2011, Paprotka, et al. reported that XMRV likely originated through recombination between 2 endogenous murine retroviruses, PreXMRV - 1 and PreXMRV - 2, during in vivo passaging of the human prostate cancer xenograft CWR - R1, resulting in establishment of the XMRV - infected 22Rv1 cell line [38
In 2011, Paprotka, et al. reported that XMRV likely originated through recombination between 2
endogenous murine
retroviruses, PreXMRV - 1 and PreXMRV - 2, during
in vivo passaging of the human prostate cancer xenograft CWR - R1, resulting in establishment of the XMRV - infected 22Rv1 cell line [38
in vivo passaging of the human prostate cancer xenograft CWR - R1, resulting
in establishment of the XMRV - infected 22Rv1 cell line [38
in establishment of the XMRV - infected 22Rv1 cell line [38].
GB:
Endogenous Retroviruses (ERV) are real and exist
in various forms
in nearly all living things.
Q:
In Darwin's Radio, you wrote about the evolution of a new human species that is triggered by an HERV, or Human Endogenous Retrovirus — which, if I understand correctly, is a kind of ancient virus that has entered into human DNA and persisted there in a dormant state for hundreds of thousands, if not millions, of year
In Darwin's Radio, you wrote about the evolution of a new human species that is triggered by an HERV, or Human
Endogenous Retrovirus — which, if I understand correctly, is a kind of ancient virus that has entered into human DNA and persisted there
in a dormant state for hundreds of thousands, if not millions, of year
in a dormant state for hundreds of thousands, if not millions, of years.