«Genes behind aggressive ovarian,
endometrial cancers identified.»
Not exact matches
Moreover, analysis of HAND2 methylation in
endometrial secretions collected from women with postmenopausal bleeding (which can be a symptom of
endometrial cancer) accurately
identified individuals with early stage
cancer.
Using a new bioinformatics tool, they
identified HAND2 as a differential methylation hotspot in
endometrial cancer.
We
identified patients with mutations that predict phenomenal outcomes in the disease; this is a group of women with
endometrial cancer who won't need the financial, physical or emotional toll of chemotherapy at all — they're patients who are probably cured by surgery alone.
The investigators
identified evidence of HRD - related mutations in 11.61 percent of them, with the highest concentration of mutations in
endometrial cancer, gliomas, and ovarian
cancers (38, 15 and 12 percent respectively).
In addition, the study, led by investigators in The
Cancer Genome Atlas (TCGA) Research Network, revealed four novel tumor subtypes, while also identifying genomic similarities between endometrial and other cancer types, including breast, ovarian, and colorectal ca
Cancer Genome Atlas (TCGA) Research Network, revealed four novel tumor subtypes, while also
identifying genomic similarities between
endometrial and other
cancer types, including breast, ovarian, and colorectal ca
cancer types, including breast, ovarian, and colorectal
cancers.
The Career Enhancement Program (CEP) is designed to
identify, recruit and mentor both junior and established scientists, including underrepresented investigators (minorities and women), for performing translational research in
endometrial cancer.
Oral Abstract Presentations Amy Shealy — «Novel Microduplication of 12q13.12 Including TUBA1A and DHH Detected in a Boy with Abnormal Brain MRI Findings, Cryptorchidism, Urethral Stricture and Pubertal Delay» Marissa Smith — «Expanding Genetic Counseling Services to an Executive Health Program:
Identifying Risk for Genetic Disease in a Low - Risk Population» Jessi Moline — «Approach to Systematic Screening of
Endometrial Cancers for Lynch Syndrome: the Cleveland Clinic Experience» Brandie Leach — «A Time Study of Genetic Counselor Only versus Traditional Care Genetic Counselor / Geneticist Patient Care in a
Cancer Genetics Setting» Jill Polk — «Ethico - legal Obligations in Hereditary Diffuse Gastric
Cancer Kindred with Novel CDH1 Mutation»