Pharmacokinetics and
endometrial tissue levels of progesterone after administration by intramuscular and vaginal routes: a comparative study.
Not exact matches
[17] Over time, high
levels of uninhibited estrogen can lead to
endometrial hyperplasia, or overgrowth of
tissue in the uterus.
The researchers found that HAND2 methylation is already increased in premalignant
endometrial lesions (cancer - prone, abnormal - looking
tissue) compared to normal endometrium, and that a high
level of methylation predicted a poor response to progesterone treatment (which stops the growth of some pre-cancerous
endometrial lesions).
Rx: If your gyno suspects endo, she'll likely prescribe a progestin - based contraceptive, which slows the growth of
endometrial tissue, or a short course of Lupron, which reduces estrogen
levels.
Endometriosis is one of the most common gynecological problems affecting an estimated 5.5 million women in North America, but this condition may occur at a subclinical
level in half of all women following the Western diet, as discovered by autopsy.1 This disease occurs when the
endometrial tissues lining the inside of the uterus spread outside of the uterus and become attached to the ovaries, fallopian tubes, the bowels and other internal abdominal parts.