Sentences with phrase «endonuclease gene»

Next, a copy of the homing endonuclease gene with its surrounding DNA inserts itself into the gap as the cell heals the breach.

Burt's notion was to domesticate a microbial family of selfish elements called homing endonuclease genes.

Not exact matches

Those genes make endonucleases — DNA - cutting enzymes that target one spot in an organism's entire genetic catalog, or genome.

Harvard's Esvelt was among the first to recognize that CRISPR is essentially an ultraflexible homing endonuclease that could easily be turned into a gene drive.

To put his gene theory into practice, all Burt and his colleagues had to do was reengineer a homing endonuclease to cut a certain spot in a mosquito's genome.

In addition to homing endonucleases, scientists have been tinkering with two artificial protein systems as programmable gene - editing tools.

The RNA - guided endonuclease Cas9 is a versatile genome - editing tool with a broad range of applications from therapeutics to functional annotation of genes.

Critically, gesicles do not result in persistence of the Cas9 endonuclease, which in turn reduces the chances of off - target effects and provides precise control of the dose and timing of gene editing.

Introduction of DNA double - strand breaks by site - specific endonucleases called meganucleases is being successfully used to target endogenous genes in human cells.