Structure of the γ - D - glutamyl - L - diamino
acid endopeptidase YkfC from Bacillus cereus in complex with L - Ala - γ - D - Glu: insights into substrate recognition by NlpC / P60 cysteine peptidases.
In their resting saliva, sensitive subjects had higher amounts
of endopeptidases, enzymes that cut up proteins, than non-sensitive subjects.
Matrix metalloproteinases (MMPs) are zinc -
dependent endopeptidases, responsible for the degradation of the extracellular matrix (ECM).
Ye's lab has been investigating an enzyme called AEP (
asparagine endopeptidase), which he provocatively calls «delta secretase.»
A group of proteases known as SENPs are involved in both the activation of SUMO precursors (
endopeptidase cleavage) and deconjugation of the targets (isopeptidase cleavage).
These advanced digestive enzyme formulations provide a wide array of enzymes active across a broad pH range (2 to 12) including amylases (amylase, alpha - amylase and glucoamylase), disaccharidases (lactase, sucrase / invertase and maltase), acid, alkaline and neutral proteases, protease / peptidase complex
with endopeptidase, exopeptidase and dipeptidyl peptidase - IV activities, Serratia peptidase, pullulanase, cellulase, phytase, and lipase.
Structural Basis of Murein Peptide Specificity of a gamma - D - Glutamyl - L - Diamino
Acid Endopeptidase.
For example, prolyl -
endopeptidase, from the Aspergillus niger fungus, shows promise in helping gluten - intolerant individuals.
Structures of a bifunctional cell wall hydrolase CwlT containing a novel bacterial lysozyme and an NlpC / P60 DL -
endopeptidase.
Gluten Manager ™ is uniquely designed digestive enzyme that includes
both endopeptidase and exopeptidase activity in the form of Tolerase ® G and dipeptidyl - peptidase IV (also known as DPP - IV).
Specifically, green tea was shown to have a positive effect on mice who lacked
the endopeptidase neprilysin, or NEP for short (2).