Sentences with phrase «endophenotype of»

Sleep endophenotypes of schizophrenia: slow waves and sleep spindles in unaffected first - degree relatives

Influence of sex and stress exposure across the lifespan on endophenotypes of depression: focus on behavior, glucocorticoids, and hippocampus

Endophenotypes of ASD at the neural systems level may offer insight into the pathophysiology and psychopathology of ASD by indicating components of complex social behaviors that lie closer to specific genetic factors that confer ASD risk.

Both of the putative information processing mechanisms that facilitate the storage and transmission of cultural values of individualism and collectivism described above are considered intermediate phenotypes or endophenotypes of affective disorders (Canli et al. 2006; Caspi & Moffitt 2006).

Not exact matches

Heritability of glaucoma and glaucoma - related endophenotypes: systematic review and meta - analysis protocol

Future research is needed to further determine the role that endophenotypes play in the transmission and maintenance of cultural values, practices and beliefs.

Hence, the functional utility of endophenotypes associated with the serotonin transporter gene may systematically vary as a function of cultural context.

We suggest that these endophenotypes may confer varying degrees of advantage or disadvantage to individuals depending on the cultural context.

Gottesman and Gould describe the rationale behind the concept of endophenotype as providing relatively straightforward and more elementary phenomena as opposed to behavioural phenotypes and therefore require fewer numbers of genes to produce variations in these traits as opposed to behavioural phenotypes or psychiatric diagnoses.24 These studies include associations of cortisol, as end - product of HPA - axis activity, 25 — 27 autonomic nervous system functioning, 28 and neuropsychological characteristics29 with various mental health problems.

Endophenotypes characterized by anxious attachment, poor impulse control, and hyperactive stress response can impact health behaviors and mental health and contribute to the development of many different chronic diseases including obesity, diabetes, and cardiovascular disease (Duric et al. 2016).

These so - called endophenotypes represent intermediate, subclinical - phased transitions toward a fully manifest phenotypic expression of a disease or disorder (John and Lewis 1966; Gottesman and Gould 2003).