Sentences with word «endothelial»

The word "endothelial" refers to the inner lining of blood vessels, such as the arteries and veins in our body. It is crucial for maintaining the health and function of these blood vessels, allowing blood to flow smoothly throughout the body. Full definition
The researchers then differentiated the iPS cells into endothelial cells, which line the interior of the heart and blood vessels, before transplantation.
More recently, we have started to investigate the role of arachidonic acid P450 epoxygenases in the control of endothelial cell function in vitro and tumorigenesis in vivo.
Alpha - lipoic Acid Improves Vascular Endothelial Function in Patients with Type 2 Diabetes: A Placebo - controlled Randomized Trial Eur J Clin Invest.
Chairs: Jozef Dulak, Jagiellonian University and Shahin Rafii, Weill Cornell Medical College Karen K. Hirschi, Yale School of Medicine Role of vascular endothelial cells in stem cell generation and maintenance Ann Zovein, University of California, San Francisco Cell fate decisions in hemogenic endothelium (Stem Cells I under Cells and Vascular Beds)
The siRNA can also cause side effects in endothelial cells of other organs, which don't need treatment, when administered to the whole body.
The protein analyses revealed elevated levels of vascular endothelial growth factor, or VEGF, that correlated with moderate cases of the disease.
The study concluded that including nuts within a healthy dietary pattern may have favorable effects on endothelial dysfunction, which is associated with cardiovascular disease.
Luster's team hopes to further investigate the characteristics of joints that underlie the critical role of C5a in initiating type III hypersensitivity and whether specific molecules expressed on endothelial cells lining joints play a role in transporting C5a and chemokines from the joint space into adjacent blood vessels.
Aerobic exercise overcomes the age - related insulin resistance of muscle protein metabolism by improving endothelial function and Akt / mammalian target of rapamycin signaling.
In this study, extracted bone marrow cells were shipped to NeoStem's facility and a marker for endothelial progenitor cells called CD34 was used to select progenitor cells before cells were returned for intracoronary injection.
Metabolic syndrome can lead to arteriosclerosis by endothelial dysfunction, and increases the risk for myocardial and cerebral infarction.
In fact, several of the best characterized anti-angiogenic compounds were initially detected and selected for their capability to interfere with endothelial cell growth.
Well, it's also been shown to protect the arteries from endothelial dysfunction in animal studies.
More broadly, the researchers call «for additional research on arthropod - borne pathogens whose vectors share similar blood - feeding strategies and may also impair endothelial barrier function.»
«It appears that injury itself can induce fibroblasts to change into endothelial cells so the heart heals better.
Further studies present an association in women between the stress level and the activation of the vascular endothelial nitric oxide (NO) system, as well as with the carotid intima media thickness, suggesting a close link to stress induced cardiovascular dysfunction in women (99).
The patient example here used to discredit the virtues of the plant based intervention approach would have likely showed massive endothelial damage from the decades of high animal protein and artery injuring foods, in fact the plant based intervention at the late stage of his chronic illness may have actually improved blood work and perhaps added some time to this patients life although it is not mentioned here.
«What's interesting is that by changing the chemistry of the nanoparticle you can affect delivery to different parts of the body, because the other formulations we've worked on are very potent for hepatocytes but not so potent for endothelial tissues,» Anderson says.
Samples of central and peripheral human corneal endothelial tissue were obtained as described above.
Fibroblasts (red) express endothelial markers (green), making the heart cells in mice appear yellow.
These cells were then grown in the laboratory under special conditions to select for stem - like cells called endothelial progenitor cells.
Modulating ECM assembly to alter tumor vascular barrier function Weilan Ye, Genentech Lymphangiogenesis and lymphatic endothelial barrier as targets in regenerative medicine Giorgia Jurisic, Novartis Wnt / beta - catenin signaling as a therapeutic target for blood - brain barrier repair in neurological disorders Dritan Agalliu, Columbia University Somatic mutations in hematopoietic cells contribute to cardiovascular disease: New mechanisms, new targets Kenneth Walsh, Boston University
A connecting hinge represses the activity of endothelial NO synthase.
He was suffering from a disease called corneal endothelial dystrophy (CED) that causes premature degeneration of the critical cells that pump fluid out of the cornea.
Expansion and maintenance of human embryonic stem cell - derived endothelial cells by TGFbeta inhibition is Id1 dependent.
Cornea buttons were mounted on an artificial anterior chamber, endothelial side up.
One undesirable, yet expected outcome of angioplasty and stent placement is the disruption of the artery's endothelial layer, which forms the inner lining of the artery.
Increased coronary artery tone (via increased sympathetic nervous activity) is especially apparent within coronary segments already expressing endothelial damage.
There is evidence that lead causes endothelial dysfunction by inhibiting nitrous oxide production and damages cell membranes by creating reactive oxygen species (ROS).
Collectively, the transcription factors (ETS / GATA / SOX) not only induce vascular endothelial differentiation, but also suppress regression to an undifferentiated state and differentiation into other ectodermal or endoderm - derived cells.
Corrected - iPSCs were induced to differentiate into mature endothelial cells which expressed the F8 gene.
So what happens is the xaliproden works in a different way than a normal anti-vascular endothelial growth factor (VEGF) agent or AREDS formula in clinical trials for dry AMD — it doesn't work in the same way.
International Journal of Cardiology 133, no. 2 (2009): 145 - 41 Mark Houston, MD, What Your Doctor May Not Tell You About Heart Disease (New York: Grand Central Life & Style, Hatchette Book Group, 2012) Ibid M.A. Carluccio et al., Olive Oil and Red Wine Antioxidant Polyphenols Inhibit Endothelial Activation: Antiatherogenic Properties of Mediterranean Diet Phytochemicals.
Additionally, another study shows that the leafy, flavonoid - rich green helps enhance endothelial function, which is a marker of cardiovascular health.
Regardless of weight, women with PCOS have been shown to have higher levels of inflammatory markers such as increases in C - reactive protein (CRP), pro-inflammatory cytokines and chemokines, white blood cell count, oxidative stress, and various markers of endothelial inflammation.
A specific lung - targeting molecule is attached to the carrier's surface and the steriod, dexamethasone, an anti-inflammatory, is loaded into the nanogel, which then binds to lung endothelial cells lining the inside wall of the blood vessels where it rapidly delivers the drug.
Now, in a study published in Nature, the researchers show that the parasite binds a protein in blood vessel walls called endothelial protein C (EPCR), which is involved with regulating blood coagulation and the inflammatory response.
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