Sentences with phrase «endothelial cell apoptosis»

Therefore, it would be advisable to test the potential effects of kahweol on endothelial cell apoptosis.

Release of cytochrome c, Bax migration, Bid cleavage, and activation of caspases 2, 3, 6, 7, 8, and 9 during endothelial cell apoptosis.

Not exact matches

By contrast, DN T cells are able to mediate DTH to donor alloantigens and induce apoptosis of donor - specific corneal endothelial cells.

The present demonstration of T cell - mediated apoptosis of allogeneic corneal cells from CD4 KO mice is consistent with previous findings, which noted the presence of apoptotic keratocytes and corneal endothelial cells in rejected corneal allografts in humans and rats respectively (5, 32).

In our study, CD8 − T cells from CD4 KO rejector mice failed to display CTL or DTH activity, yet they were capable of inducing donor - specific apoptosis of corneal endothelial cells.

Rejection by CD8 + T cells does not appear to involve either allospecific CTL or DTH effector mechanisms; however, CD8 + T cells are able to induce significant apoptosis of allogeneic corneal endothelial cells.

The extensive apoptosis of allogeneic corneal endothelial cells by CD8 − T cells from CD4 KO mice was perplexing, as this cell population should not contain CD4 + cells.

Cadmium overkill: autophagy, apoptosis and necrosis signalling in endothelial cells exposed to cadmium.

However, lymphocytes isolated from recipients of either CD8 + T cells or CD8 − T cells produced significant in vitro apoptosis of donor - specific corneal endothelial cells.

Homocysteine - Induced Apoptosis in Endothelial Cells Coincides With Nuclear NOX2 and Peri-nuclear NOX4 Activity.

They include its effects on endothelial cell «differentiation» to yield tubular - like structures, endothelial and tumor cell proliferation, apoptosis, and migration, as well as its effects on extracellular matrix remodelling enzyme activities of matrix metalloproteinase - 2 (MMP - 2) and urokinase - type plasminogen activator (uPA).

Figure 2 (middle line) shows that 50 nmol kahweol induced apoptosis in a small percentage of cells but this effect did not seem to be endothelial cell specific, since only few apoptotic nuclei corresponded to endothelial cells.

Concerning the apoptosis assay, the negative effect on endothelial (HUVEC) cells is in agreement with our results in quail CAM.

Fatty acids differentially influence phosphatidylinositol 3 - kinase signal transduction in endothelial cells: impact on adhesion and apoptosis.

In addition to LOX - 1 mediated vascular inflammation, oxLDL / LOX -1 internalization triggers endothelial / vascular smooth muscle cell dysfunction, apoptosis, cellular senescence, or osteoblastic differentiation.