Not exact matches
So Daniel Anderson at the Massachusetts Institute of Technology exposed human bone marrow stem
cells to biodegradable nanoparticles carrying the human gene for vascular
endothelial growth factor (VEGF), which attracts blood vessels to
injury sites.
Working in Morrison's Neurotrauma and Repair Laboratory at Columbia Engineering, the team developed a blast
injury model using a shock tube and custom - designed sample receiver to simulate a primary blast event and applied it to an isolated, living model of the BBB that consisted of brain
endothelial cells.
«It appears that
injury itself can induce fibroblasts to change into
endothelial cells so the heart heals better.
Neutrophils recruit and activate Human
Endothelial Colony Forming
Cells at the site of vessel
injury via PSGL - 1 and L - Selectin.
A vascular
injury model using focal heat - induced activation of
endothelial cells.
Endothelial cells line the inside of all blood vessels and regulate inflammation, blood clotting following
injury and blood pressure levels.
Diabetes decreases the quantity and efficiency of EPCs (
endothelial progenitor
cells), whose function is to travel to injured areas and help with the formation of blood vessels and heal
injuries quickly.
Let's recap for a minute the steps of the making of a heart attack, though I am sure you are aware of them:
injury to the
endothelial cell leads to inflammation, which leads to oxidized cholesterol deposits, to blood clots formation and finally to a heart attack or stroke.
In the absence of inflammation or
injury to the
endothelial cell, the cholesterol would never go through the arterial wall and it would never stay there.
It also helped protect against oxidative damage that leads to brain
cell death, and reduced
injury to brain
endothelial cells in mice with high - fat diets.
In many animals, including dogs, corneal
endothelial cells have a very limited capacity to regenerate following
injury.
The reparative phase occurs within 3 to 14 days after
injury and is characterized by the cellular response of fibroblasts and
endothelial cells.