Sentences with phrase «endothelial cell proliferation»

In one study Dong quai was shown to significantly enhance endothelial cell proliferation and vascular health, indicating a potential role in supporting heart health.

We show for the first time that kahweol is an anti-angiogenic compound with inhibitory effects in two in vivo and one ex vivo angiogenesis models, with effects on specific steps of the angiogenic process: endothelial cell proliferation, migration, invasion and tube formation on Matrigel.

This is the case of the extremely selective inhibitor of endothelial cell proliferation TNP - 470, a synthetic analog of fumagillin with enhanced anti-angiogenic properties [22], [23].

Many other natural anti-angiogenic compounds inhibit endothelial cell proliferation [9], [10], [24], [25].

Bartonella - induced endothelial cell proliferation is mediated by release of calcium from intracellular stores.

The resulting endothelial cell lines described in this study retain their phenotype after repeated passage, require minimal nutritional support and, importantly, may be useful for identifying factors that regulate endothelial cell proliferation and tumor cell adhesion in different anatomical regions.

Not exact matches

The rate of cell proliferation varied only slightly between the different endothelial cell lines (Fig. 3) ⇓.

We have observed on several occasions that, for the majority of endothelial cell lines, the transfer to 37 °C conditions for 72 h correlated with a 50 % reduction in cell proliferation, a value that continued to decrease with time.

Activation of endothelial cells elicits a complex series of responses that include the elaboration of proteolytic enzymes, migration, and proliferation.

Blake DA, Yu H, Young DL, Caldwell DR. Matrix stimulates the proliferation of human corneal endothelial cells in culture.

MicroRNA - 195 regulates proliferation, migration, angiogenesis and autophagy of endothelial progenitor cells by targeting GABARAPL1.

MicroRNA - 24 inhibits the proliferation and migration of endothelial cells in patients with atherosclerosis by targeting importin - a3 and regulating inflammatory responses.

MicroRNA - 138 inhibits hypoxia - induced proliferation of endothelial progenitor cells via inhibition of HIF - 1a - mediated MAPK and AKT signaling.

They include its effects on endothelial cell «differentiation» to yield tubular - like structures, endothelial and tumor cell proliferation, apoptosis, and migration, as well as its effects on extracellular matrix remodelling enzyme activities of matrix metalloproteinase - 2 (MMP - 2) and urokinase - type plasminogen activator (uPA).

Angiogenesis involves local proliferation of endothelial cells in response to an angiogenic stimulus.

Figure 4 shows the mean survival curves obtained with the MTT assay in human umbilical vein endothelial cells (HUVEC), under conditions of normal and low proliferation rates (20 % and 2 % of FBS).

The vasculature can influence neural stem cell proliferation and differentiation by providing a local source of signaling molecules secreted from endothelial cells (1) as well as by delivering systemic regulatory factors (2).

Vascular endothelial dysfunction promotes vasoconstriction and favors platelet aggregation, white blood cell adhesion, and smooth muscle cell proliferation.