In a collaborative effort between the Gladstone laboratories of Benoit Bruneau, PhD, Katherine Pollard, PhD, and Dr. Srivastava, the scientists used stem cell technology to make large amounts of
endothelial cells from patients with CAVD, comparing them to healthy cells and mapping their genetic and epigenetic changes as they developed into valve cells.
Not exact matches
Another approach might be to selectively remove CD11b leukocytes
from the blood circulation so that they are not available to adhere to the blood - nerve barrier
endothelial cells in
patient's nerves.
In a report published online in Diabetes, the authors showed that RUNX1 was upregulated in vascular
endothelial cells obtained
from fibrovascular membranes in PDR
patients.
Finally, analyses of transcriptomic data revealed increased FGF2 expression in ductal,
endothelial, and stellate
cells in pancreas
from T2D
patients, whereas FGFR1, SOX, 9 and HES1 expression increased in islets
from T2D
patients.