Sentences with phrase «endothelial dysfunction in»

Tarkun I, Arslan BC, Canturk Z, Turemen E, Sahin T, Duman C. Endothelial dysfunction in young women with polycystic ovary syndrome: relationship with insulin resistance and low - grade chronic inflammation.

Well, it's also been shown to protect the arteries from endothelial dysfunction in animal studies.

Our findings suggest that selenium restores a normal metabolic profile and ameliorates vascular responses and endothelial dysfunction in diabetes by regulating antioxidant enzyme and nitric oxide release.

Coffee consumption and markers of inflammation and endothelial dysfunction in healthy and diabetic women.

Coffee with a high content of chlorogenic acids and low content of hydroxyhydroquinone improves postprandial endothelial dysfunction in patients with borderline and stage 1 hypertension.

Consuming this algae reverses endothelial dysfunction in metabolic syndrome.

Many studies have confirmed spirulina's antihypertensive effect, so a 2013 study dug deeper and set out to determine whether or not spirulina's active pigment compound, phycocyanin, could improve endothelial dysfunction in metabolic syndrome.

Interferon - gamma induced adipose tissue inflammation is linked to endothelial dysfunction in type 2 diabetic mice.

Therefore, the primary novelty of the discoveries reported here is that programming by prenatal chronic hypoxia of cardiac and vascular dysfunction in adulthood follows the induction of oxidative stress in the fetal heart and vasculature, and that cardiac and endothelial dysfunction in adulthood can both be prevented by maternal treatment with antioxidants during pregnancy.

Not exact matches

We also demonstrate that NS1 from DENV1, DENV2, DENV3, and DENV4 triggers endothelial barrier dysfunction, causing increased permeability of human endothelial cell monolayers in vitro.

It is interesting that the balance of redox modulation of vascular tone, imposed by the O2 • −: NO ratio, may be tipped in either direction to promote disequilibrium, as maternal treatment with vitamin C in normoxic pregnancy also promoted endothelial dysfunction.

Here, we tested the hypothesis that oxidative stress in the fetal heart and vasculature underlies the molecular basis through which prenatal hypoxia contributes to the developmental programming of cardiac and endothelial dysfunction.

Role of the endothelial - derived endogenous anti-inflammatory factor Del - 1 in inflammation - mediated adrenal gland dysfunction.

Endothelial dysfunction: a critical determinant in inflammation - associated adrenal insufficiency?

Highly active antiretroviral therapy drug combination induces oxidative stress and mitochondrial dysfunction in immortalized human blood — brain barrier endothelial cells.

Reversing vascular dysfunction in rheumatoid arthritis: improved augmentation index but not endothelial function with peroxisome proliferator - activated receptor γ agonist therapy.

Further studies present an association in women between the stress level and the activation of the vascular endothelial nitric oxide (NO) system, as well as with the carotid intima media thickness, suggesting a close link to stress induced cardiovascular dysfunction in women (99).

Susan Amara, USA - «Regulation of transporter function and trafficking by amphetamines, Structure - function relationships in excitatory amino acid transporters (EAATs), Modulation of dopamine transporters (DAT) by GPCRs, Genetics and functional analyses of human trace amine receptors» Tom I. Bonner, USA (Past Core Member)- Genomics, G protein coupled receptors Michel Bouvier, Canada - Molecular Pharmacology of G protein - Coupled Receptors; Molecular mechanisms controlling the selectivity and efficacy of GPCR signalling Thomas Burris, USA - Nuclear Receptor Pharmacology and Drug Discovery William A. Catterall, USA (Past Core Member)- The Molecular Basis of Electrical Excitability Steven Charlton, UK - Molecular Pharmacology and Drug Discovery Moses Chao, USA - Mechanisms of Neurotophin Receptor Signaling Mark Coles, UK - Cellular differentiation, human embryonic stem cells, stromal cells, haematopoietic stem cells, organogenesis, lymphoid microenvironments, develomental immunology Steven L. Colletti, USA Graham L Collingridge, UK Philippe Delerive, France - Metabolic Research (diabetes, obesity, non-alcoholic fatty liver, cardio - vascular diseases, nuclear hormone receptor, GPCRs, kinases) Sir Colin T. Dollery, UK (Founder and Past Core Member) Richard M. Eglen, UK Stephen M. Foord, UK David Gloriam, Denmark - GPCRs, databases, computational drug design, orphan recetpors Gillian Gray, UK Debbie Hay, New Zealand - G protein - coupled receptors, peptide receptors, CGRP, Amylin, Adrenomedullin, Migraine, Diabetes / obesity Allyn C. Howlett, USA Franz Hofmann, Germany - Voltage dependent calcium channels and the positive inotropic effect of beta adrenergic stimulation; cardiovascular function of cGMP protein kinase Yu Huang, Hong Kong - Endothelial and Metabolic Dysfunction, and Novel Biomarkers in Diabetes, Hypertension, Dyslipidemia and Estrogen Deficiency, Endothelium - derived Contracting Factors in the Regulation of Vascular Tone, Adipose Tissue Regulation of Vascular Function in Obesity, Diabetes and Hypertension, Pharmacological Characterization of New Anti-diabetic and Anti-hypertensive Drugs, Hypotensive and antioxidant Actions of Biologically Active Components of Traditional Chinese Herbs and Natural Plants including Polypehnols and Ginsenosides Adriaan P. IJzerman, The Netherlands - G protein - coupled receptors; allosteric modulation; binding kinetics Michael F Jarvis, USA - Purines and Purinergic Receptors and Voltage-gated ion channel (sodium and calcium) pharmacology Pain mechanisms Research Reproducibility Bong - Kiun Kaang, Korea - G protein - coupled receptors; Glutamate receptors; Neuropsychiatric disorders Eamonn Kelly, Prof, UK - Molecular Pharmacology of G protein - coupled receptors, in particular opioid receptors, regulation of GPCRs by kinasis and arrestins Terry Kenakin, USA - Drug receptor pharmacodynamics, receptor theory Janos Kiss, Hungary - Neurodegenerative disorders, Alzheimer's disease Stefan Knapp, Germany - Rational design of highly selective inhibitors (so call chemical probes) targeting protein kinases as well as protein interaction inhibitors of the bromodomain family Andrew Knight, UK Chris Langmead, Australia - Drug discovery, GPCRs, neuroscience and analytical pharmacology Vincent Laudet, France (Past Core Member)- Evolution of the Nuclear Receptor / Ligand couple Margaret R. MacLean, UK - Serotonin, endothelin, estrogen, microRNAs and pulmonary hyperten Neil Marrion, UK - Calcium - activated potassium channels, neuronal excitability Fiona Marshall, UK - GPCR molecular pharmacology, structure and drug discovery Alistair Mathie, UK - Ion channel structure, function and regulation, pain and the nervous system Ian McGrath, UK - Adrenoceptors; autonomic transmission; vascular pharmacology Graeme Milligan, UK - Structure, function and regulation of G protein - coupled receptors Richard Neubig, USA (Past Core Member)- G protein signaling; academic drug discovery Stefan Offermanns, Germany - G protein - coupled receptors, vascular / metabolic signaling Richard Olsen, USA - Structure and function of GABA - A receptors; mode of action of GABAergic drugs including general anesthetics and ethanol Jean - Philippe Pin, France (Past Core Member)- GPCR - mGLuR - GABAB - structure function relationship - pharmacology - biophysics Helgi Schiöth, Sweden David Searls, USA - Bioinformatics Graeme Semple, USA - GPCR Medicinal Chemistry Patrick M. Sexton, Australia - G protein - coupled receptors Roland Staal, USA - Microglia and neuroinflammation in neuropathic pain and neurological disorders Bart Staels, France - Nuclear receptor signaling in metabolic and cardiovascular diseases Katerina Tiligada, Greece - Immunopharmacology, histamine, histamine receptors, hypersensitivity, drug allergy, inflammation Georg Terstappen, Germany - Drug discovery for neurodegenerative diseases with a focus on AD Mary Vore, USA - Activity and regulation of expression and function of the ATP - binding cassette (ABC) transporters

Edward Bullmore, UK Robert Dow, UK Garrett Fitzgerald, USA - Prostanoid biology and the role of peripheral molecular clocks in cardiovascular biology, metabolism and aging Alex Phipps, UK - Oncology, Clinical Pharmacology, Biologics and Immunotherapy Patrick du Souich, Canada - Cytochrome P450, membrane carriers, disease, inflammation, rational use of drugs, clinical pharmacology David J. Webb, UK - hypertension, chronic kidney disease, endothelial function and dysfunction, arterial stiffness, health technology assessment, medicines regulation Don Birkett, Australia - Clinical pharmacology / pharmacokinetics and drug utilisation

Sep. 13, 2016 — High levels of blood markers for vascular endothelial dysfunction were associated with longer periods of confusion in ICU patients, Vanderbilt researchers have discovered.

There are also studies that show immediate dysfunction in your arteries, also called endothelial function.

In the present analysis, we also assessed the correlations between magnesium intake and the concentrations of 3 endothelial adhesion molecules, which are up - regulated in the early cascade of endothelial dysfunctioIn the present analysis, we also assessed the correlations between magnesium intake and the concentrations of 3 endothelial adhesion molecules, which are up - regulated in the early cascade of endothelial dysfunctioin the early cascade of endothelial dysfunction.

Plasma concentrations of biomarkers of inflammation and endothelial dysfunction by quintile (Q) of dietary magnesium intake in 657 apparently healthy women in the Nurses» Health Study1

It seems likely that the observed associations between magnesium intake and markers of inflammation and endothelial dysfunction may, at least in part, reflect the direct effect of magnesium intake on glucose and insulin homeostasis.

Effect of a Mediterranean - style diet on endothelial dysfunction and markers of vascular inflammation in the metabolic syndrome: a randomized trial

This comes in the wake of over a decade worth of research showing that chocolate and / or cocoa lowers blood pressure, prevents or ameliorates endothelial dysfunction (a primary contributor to atherosclerosis), protects against coronary artery disease, reduces stroke risk, prevents cholesterol oxidation (which converts healthy lipoproteins into artherogenic ones), to name only 5 of 70 + potential health benefits associated with its regular consumption.

In 2010 a study confirmed that in the early stages of menopause women have higher risks of endothelial dysfunctioIn 2010 a study confirmed that in the early stages of menopause women have higher risks of endothelial dysfunctioin the early stages of menopause women have higher risks of endothelial dysfunction.

In addition to the other studies shared, eggs cause endothelial dysfunction immediately after consumption, how can we call this healthy?

In addition to LOX - 1 mediated vascular inflammation, oxLDL / LOX -1 internalization triggers endothelial / vascular smooth muscle cell dysfunction, apoptosis, cellular senescence, or osteoblastic differentiation.

Effect of benfotiamine on advanced glycation endproducts and markers of endothelial dysfunction and inflammation in diabetic nephropathy.

Endothelial cell activation, vascular smooth muscle dysfunction, oxidative stress, and inflammation, mechanisms which underlie heart disease, diabetes, and hypertension, are all variables which can precipitate or perpetuate immune imbalances in autoimmune disease.

Endothelial dysfunction is often seen in patients with coronary artery disease, diabetes mellitus, hypertension, and hypercholesterolemia.

In conclusion, alpha - lipoic acid may reduce the risk of vascular endothelial dysfunction.

Exercise has a «protective effect» against erectile dysfunction by reducing endothelial apoptosis in your body.

High homocysteine levels can result in endothelial dysfunction (a narrowing of the arteries) which in turn is believed to be a precursor of atherosclerosis.

Previous studies have indicated that postprandial hyperglycemia and acute glycemic load result in inflammatory responses and endothelial dysfunction (27).

If it's the one about endothelial dysfunction, the article title is Impaired endothelial function following a meal rich in used cooking fat.

NEW YORK (Reuters Health)- A diet rich in fish, fruit, and vegetables may reduce endothelial dysfunction and low - grade inflammation and hence lead to less cardiovascular disease (CVD), according to Dutch researchers.

A diet rich in fish, fruit, and vegetables may reduce endothelial dysfunction and low - grade inflammation and hence lead to less cardiovascular disease (CVD), according to Dutch researchers

«Endothelial dysfunction and low - grade inflammation play important roles in the development of CVD,» the investigators wrote in their December 31 online paper in The Journal of Nutrition.

We will continue to explore Chrysalin's therapeutic value in tissues and diseases exhibiting endothelial dysfunction as well as the science behind and potential of Chrysalin.