Sentences with phrase «endothelial growth factor»

Switching Anti-Vascular Endothelial Growth Factors in Refractory Neovascular Age - Related Macular Degeneration.
Lithium Upregulates Vascular Endothelial Growth Factor in Brain Endothelial Cells and Astrocytes
One class of drugs, called vascular endothelial growth factor inhibitors, for example, is designed to thwart the growth of abnormal blood vessels in the eye.
Pancreatic cyst fluid is tested for a biomarker, a specific isoform of vascular endothelial growth factor A, or VEGF - A.
The anti-vascular endothelial growth factor drugs ranibizumab and aflibercept, used to treat vision loss from diabetic macular edema (DME), and approximately 20 to 30 times more expensive than bevacizumab, are not cost - effective for treatment of DME compared to bevacizumab unless their prices decrease substantially, according to a study published online by JAMA Ophthalmology.
High serum vascular endothelial growth factor level is an adverse prognostic factor for high - risk diffuse large B - cell lymphoma patients treated with dose - dense chemoimmunotherapy.
Vascular endothelial growth factor signaling is necessary for expansion of medullary microvessels during postnatal kidney development.
Park, Y. S., Kim, N. H. & Jo, I. Hypoxia and vascular endothelial growth factor acutely up - regulate angiopoietin - 1 and Tie2 mRNA in bovine retinal pericytes.
A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer.
Vikas Gulati, MD Truhlsen Eye Institute, University of Nebraska Medical Center, Omaha, Nebraska Funding provided by a grant from The Alcon Foundation Project: Effect of Vascular Endothelial Growth Factor Blockers on Aqueous Humor Dynamics
Reishi mushroom contains special polysaccharides called beta - glucans said to fight cancer cells by suppressing endothelial growth factor, support the immune system, and enhance cytotoxic receptors (NKG2D / NCR) killer cells.
«Flavonoids and Vitamin E Reduce the Release of the Angiogenic Peptide Vascular Endothelial Growth Factor from Human Tumor Cells».
Vascular endothelial growth factor concentrations in body cavity effusions in dogs.
Nintedanib, in addition to blocking vascular endothelial growth factor receptors (VEGFR) and platelet derived growth factor receptors (PDGFR), also acts on fibroblast growth factor receptors (FGFR), which makes it different to classical angiogenesis inhibitors.
PURPOSE To summarize the findings of long - term outcomes of anti-vascular endothelial growth factor (VEGF) therapy (≥ 36 months) in patients with exudative age - related macular degeneration.
These treatments involve regular injection of vascular endothelial growth factor inhibitors (anti-VEGF) into the eye.
First - line combination therapy with the programmed death ligand 1 (PD - L1) inhibitor avelumab and the vascular endothelial growth factor receptor tyrosine kinase inhibitor axitinib resulted in encouraging antitumor activity in patients with previously untreated renal cell carcinoma (RCC) and had a manageable toxicity profile, according to the results of the JAVELIN Renal 100 study published in Lancet Oncology.
The protein analyses revealed elevated levels of vascular endothelial growth factor, or VEGF, that correlated with moderate cases of the disease.
The advent of intravitreous (in the vitreous, the fluid behind the lens in the eye) anti-vascular endothelial growth factor (VEGF) injections to treat common causes of vision loss, such as exudative (wet) age - related macular degeneration (AMD) and diabetic macular edema has improved visual outcomes for many patients.
So Daniel Anderson at the Massachusetts Institute of Technology exposed human bone marrow stem cells to biodegradable nanoparticles carrying the human gene for vascular endothelial growth factor (VEGF), which attracts blood vessels to injury sites.
The cannabinoids inhibited the expression of several genes critical to angiogenesis known as the VEGF (vascular endothelial growth factor) pathway.
«Moreover, we found that vascular endothelial growth factor (VEGF) plays an important role in cell growth and survival.
This happens because the loss of blood flow in a vessel causes the local oxygen level to drop, which stimulates local production of vascular endothelial growth factor, or VEGF, a protein which in most tissues causes the growth of new blood vessels to repair damage.
And they incorporated into the gel a protein known as vascular endothelial growth factor (VEGF), which encourages the growth of blood vessels into the transplanted cells.
A critical discovery in this research was finding that the novel progenitor has a receptor protein on its cell surface called KDR, or vascular endothelial growth factor receptor 2, which until now, was thought to be restricted to endothelial cells that form vessels, the progenitors for endothelial cells and the progenitors blood cells.
Among dozens of mouse studies, he presented work led by Moderna Co-Founder Kenneth Chien, then at Harvard Medical School in Boston, showing that mice recovering from induced heart attacks survived longer and had stronger hearts when injected with mRNA encoding a protein that drives blood vessel formation — vascular endothelial growth factor (VEGF).
This is very different mechanism of action than other agents that also effect angiogenesis by inhibiting vascular endothelial growth factor (VEGF) such as bevacizumab (Avastin; Genentech).
Traditionally, scientists have thought that the protein Vascular Endothelial Growth Factor (VEGF) was responsible for guiding the angioblasts to the midline of the body for blood vessel formation.
This protein binds to two growth factors — vascular endothelial growth factor (VEGF) and placental growth factor (PlGF)-- that promote the development of new blood vessels and the maintenance of the vascular system.
Vascular endothelial growth factor A (VEGF - A) is a protein associated with promotion of new blood vessel formation.
The findings are reported in «Vascular Endothelial Growth Factor, a Novel and Highly Accurate Pancreatic Fluid Biomarker for Serous Pancreatic Cysts» online in the Journal of the American College of Surgeons.
Cheeks and gums tend to heal more quickly than skin, without scarring, thanks to proteins in saliva like vascular endothelial growth factor that promote the formation of blood vessels.
For the first time ever, the researchers have shown that NK cells produce a factor called VEGF - A (Vascular Endothelial Growth Factor A) that promotes tumor growth.
For example, leader cells secrete more VEGF (vascular endothelial growth factor) than followers do.
Linking the vascular endothelial growth factor (VEGF) genetic pathway with a specific disease characteristic among SLE patients represents an important step towards unravelling the genetic basis of different SLE clinical presentations.
Specifically, two factors were applied: the Vascular Endothelial Growth Factor (VEGF) and the Glial Cell - derived Neurotrophic Factor (GDNF).
They then turned to neurochemical studies, including lactate, glutamate and glutamine metabolism, effects on the hypothalamic - pituitary - adrenal (HPA) axis through cortisol secretion, and neurotrophins such as brain - derived neurotrophic factor (BDNF), insulin - like growth factor 1 (IGF - 1), and vascular endothelial growth factor (VEGF).
Due to the lack of oxygen in the cancer cells, VEGF - A (Vascular Endothelial Growth Factor) is formed and this promotes the formation of new blood vessels to supply the tumor.
Bevacizumab, a monoclonal antibody, is an angiogenesis inhibitor that targets a chemical signal, vascular endothelial growth factor A (VEGF - A).
The newly developed porous films do not require an addition of costly growth factors, and they are capable of adsorbing vascular endothelial growth factors (VEGFs) that occur naturally in the body and taking them into the film materials.
They discovered that the placentas of preeclampsia patients showed more activity in the gene for sFlt1, a protein that blocks the effects of vascular endothelial growth factor and placental growth factor, two key proteins necessary for an adequate placental development and normal blood vessel health.
During the creation of new blood vessels, the vascular endothelial growth factor (VEGF) protein differentiates stem cells into vascular endothelial cells and stimulates them to create new blood vessels.
It is an inhibitor of a vascular endothelial growth factor, a cytokine called VEGF.
Earlier studies by Basu and others have shown that dopamine blocks the growth of new blood vessels in tumors by inhibiting the action of vascular endothelial growth factor - A (VEGF - A).
Instead, says Martinez - Lavin, elevated levels of prostaglandins might somehow enable another molecule called vascular endothelial growth factor (VEGF) to cause clubbing.
High Serum Vascular Endothelial Growth Factor (VEGF) Level Is An Adverse Prognostic Factor In High Risk Diffuse Large B - Cell Lymphoma (DLBCL) Patients Treated with Dose - Dense Chemoimmunotherapy and Systemic CNS Prophylaxis.
This happens because the loss of blood flow in a blood vessel causes the local oxygen level to drop, which stimulates local production of vascular endothelial growth factor, or VEGF, a protein that in most tissues causes the growth of new blood vessels to repair damage.
A marker in bile known as vascular endothelial growth factor (VEGF) plays an important role in the growth of cancerous tumors according to new research presented at the 78th Annual Scientific Meeting of the American College of Gastroenterology.

Phrases with «endothelial growth factor»

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