Sentences with phrase «endothelial growth factor antibody»
A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer.
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Bevacizumab, a monoclonal antibody, is an angiogenesis inhibitor that targets a chemical signal, vascular endothelial growth factor A (VEGF - A).
↵ 3 The abbreviations used are: HUVEC, human umbilical vein endothelial cell; DiI - Ac - LDL, 1,1 ′ - dioctadecyl - 3,3,3 ′, 3 ′ - tetramethyl - indocarbocyanine acetylated low - density lipoprotein; FACS, fluorescence - activated cell sorting; FGFR, fibroblast growth factor receptor; Flk, fetal liver kinase; ICAM, intercellular adhesion molecule; mAb, monoclonal antibody; PE, phycoerythrin; TNF, tumor necrosis factor; VCAM, vascular cell adhesion molecule.
A phase I trial of ramucirumab, a human monoclonal antibody against the vascular endothelial growth factor - 2 (VEGFR - 2) receptor, in children with refractory solid tumors, including CNS tumors (NCT02564198).
A phase I trial of ramucirumab, a human monoclonal antibody against the vascular endothelial growth factor - 2 (VEGFR - 2) receptor, in children with refractory solid tumors, including CNS tumors -LRB-
The use of targeting antibodies against vascular endothelial growth factor (VEGF), a protein that promotes tumor growth and spread, plus chemotherapy has prolonged disease free survival in several different tumor types in man.
In this proposal we set out to utilize our canine - derived scFv phage display platform technology to isolate canine antibody fragments that bind and neutralize Vascular Endothelial Growth Factor (VEGF).