Sentences with phrase «endothelial growth factor receptors»

Nintedanib, in addition to blocking vascular endothelial growth factor receptors (VEGFR) and platelet derived growth factor receptors (PDGFR), also acts on fibroblast growth factor receptors (FGFR), which makes it different to classical angiogenesis inhibitors.

A critical discovery in this research was finding that the novel progenitor has a receptor protein on its cell surface called KDR, or vascular endothelial growth factor receptor 2, which until now, was thought to be restricted to endothelial cells that form vessels, the progenitors for endothelial cells and the progenitors blood cells.

γ - secretase and presenilin mediate cleavage and phosphorylation of vascular endothelial growth factor receptor - 1.

Genetic Reduction of Vascular Endothelial Growth Factor Receptor 2 Rescues Aberrant Angiogenesis Caused by Epsin Deficiency.

Phase II study of cediranib (AZD 2171), an inhibitor of the vascular endothelial growth factor receptor, for second - line therapy of small cell lung cancer (NCI # 7097).

Vascular endothelial growth factor receptor, also called VEGFR, is a biomarker found in certain patients with lung cancer.

Not exact matches

↵ 3 The abbreviations used are: HUVEC, human umbilical vein endothelial cell; DiI - Ac - LDL, 1,1 ′ - dioctadecyl - 3,3,3 ′, 3 ′ - tetramethyl - indocarbocyanine acetylated low - density lipoprotein; FACS, fluorescence - activated cell sorting; FGFR, fibroblast growth factor receptor; Flk, fetal liver kinase; ICAM, intercellular adhesion molecule; mAb, monoclonal antibody; PE, phycoerythrin; TNF, tumor necrosis factor; VCAM, vascular cell adhesion molecule.

4 The downstream signaling pathways of some growth factor receptors was also intact because many of the cell lines exhibited proliferative responses to certain of the known endothelial cell mitogens.

His study highlighted a role for vascular endothelial growth factor (VEGF) in N - methyl - D - aspartate (NMDA) receptor trafficking via the activation of long - term potentiation signaling pathways at the post-synaptic sites (De Rossi et al, 2016).

A vascular endothelial growth factor - 2 receptor inhibitor enhances anti-tumor immunity through an immune - based mechanism.

A phase I trial of ramucirumab, a human monoclonal antibody against the vascular endothelial growth factor - 2 (VEGFR - 2) receptor, in children with refractory solid tumors, including CNS tumors (NCT02564198).

A phase I trial of ramucirumab, a human monoclonal antibody against the vascular endothelial growth factor - 2 (VEGFR - 2) receptor, in children with refractory solid tumors, including CNS tumors -LRB-

Reishi mushroom contains special polysaccharides called beta - glucans said to fight cancer cells by suppressing endothelial growth factor, support the immune system, and enhance cytotoxic receptors (NKG2D / NCR) killer cells.

One of these growth factors is vascular endothelial growth factor - A or VEGF, which acts by binding specific receptors on the hemangiosarcoma cells.