Sentences with phrase «endothelial progenitor»

These cells were then grown in the laboratory under special conditions to select for stem - like cells called endothelial progenitor cells.

MicroRNA - 195 regulates proliferation, migration, angiogenesis and autophagy of endothelial progenitor cells by targeting GABARAPL1.

The US scientists claim to have made progress towards this, using a «nanoscale» template into which stem cells called endothelial progenitor cells are placed.

The team then introduced short RNA molecules that deactivate a gene called Id1, which promotes angiogenesis and is active in endothelial progenitors.

The treated mice also showed a 96 percent reduction in the flow of endothelial progenitors from bone marrow to lung.

Review of «Antitumor Effects of CD40 Ligand - Expressing Endothelial Progenitor Cells Derived From Human Induced Pluripotent Stem Cells in a Metastatic Breast Cancer Model» from Stem Cells TM by Stuart P. Atkinson.

Arap W and Pasqualini R Engineered embryonic endothelial progenitor cells as therapeutic Trojan horses.

The low density culture protocol helps in generating larger number of CD133 + endothelial population from initially fewer CD133 + endothelial progenitor cells; EPCs (Figure S1).

Decreased phosphorylation of PDGFR - ß impairs the angiogenic potential of expanded endothelial progenitor cells via the inhibition of PI3K / Akt signaling.

Cardiovascular disease and renal disease for example are accelerated in patients with diabetes and AGEs have been shown to induce senescence in cell types related to these diseases, such as endothelial progenitor cells, vascular endothelial cells and renal cells.

Moreover, a substantial increase in circulating endothelial progenitor cells, which repair damaged blood vessels, was noted after consuming bread made from the ancient grain Verna.

The image shows red endothelial progenitor cells expanding and proliferating forming tumors between the green muscle fibers.

In this study, extracted bone marrow cells were shipped to NeoStem's facility and a marker for endothelial progenitor cells called CD34 was used to select progenitor cells before cells were returned for intracoronary injection.

Our data confirms that endothelial progenitors obtained from adult human blood vessels can be expanded in vitro under xenoprotein - free conditions, for potential use in endothelialization of small diameter ePTFE grafts.

Isolated endothelial progenitor cells (EPCs) were expanded in vitro under low cell density culture conditions (Figure 1A: 103 cells / cm2).

Are new blood vessels being formed from existing capillaries or from novel endothelial progenitors present in the vasculature of young mice?

There have, however, been some studies with encouraging results; for example, Chinese scientists took human endothelial progenitor cells exposed to resveratrol, and showed that telomerase activity increased.

Umbilical cord blood has a number of different types of cord stem cells, like endothelial progenitor cells, hematopoietic stem cells, and mesenchymal stem cells.

Antitumor Effects of CD40 Ligand - Expressing Endothelial Progenitor Cells Derived From Human Induced Pluripotent Stem Cells in a Metastatic Breast Cancer Model.

Embryonic endothelial progenitor cells armed with a suicide gene target hypoxic lung metastases after intravenous delivery.

To confirm if EPCs grown in culture were progenitor cells, clonogenicity of CD133 + endothelial progenitors was tested.

MicroRNA - 138 inhibits hypoxia - induced proliferation of endothelial progenitor cells via inhibition of HIF - 1a - mediated MAPK and AKT signaling.

Bone marrow contains rare cells called endothelial progenitor cells, which are thought to promote healing and recovery of blood flow.

Estradiol's benefits appear related to activation of Endothelial Progenitor Cells which invoke new collateral circulation in areas of injury.

Still, they hope to discover drugs that could put the brakes on at least some metastases by short - circuiting the ability of endothelial progenitors to respond to chemical cues sent out by tumors.

To explain the so - called angiogenic switch, or sudden growth of new blood vessels, some have pointed to endothelial progenitors, which live in bone marrow but are found in more than half of all solid tumor types, says hematology oncologist Shahin Rafii of Weill Cornell Medical College in New York City.

A team from Cold Spring Harbor Laboratory in Long Island, N.Y., reports that it staved off full - blown metastasis in mice by preventing mini-tumors in the lungs from recruiting stem cells called endothelial progenitors, which assemble into blood vessels to nourish the malignancy.

Endothelial progenitor cells (EPCs) differentiate into the cells that make up the lining of blood vessels, and so play roles in vasculogenesis and angiogenesis.

The postnatal adipose tissue contains a heterogeneous population of cells which includes adult stem cells (i.e., MSCs), endothelial progenitor cells, leukocytes, endothelial cells, and vascular smooth muscle cells.

Endothelial progenitor cells derived from induced pluripotent stem cells which target tumors can be modified to carry an anti-tumorigenic «payload» and promoter tumor growth inhibitionsy

Researchers from the laboratories of Hiroshi Y. Yoshikawa and Hideki Taniguchi had previously demonstrated the in vitro formation of a 3D transplantable liver «organ bud» from human induced pluripotent stem cells (iPSCs) co-cultured with mesenchymal and endothelial progenitors, and allows for the growth of a small vascularized and functional organ [1 - 3].

Previous attempts to achieve the same effect elsewhere had implanted cells lasting only a few days to weeks, although those studies mostly used adult stem cells, such as mesenchymal stem cells or endothelial progenitor cells, he says.

DIC images of endothelial progenitor cells (EPCs) during in vitro expansion (A) and differentiation (B).

Endothelial progenitor cells were isolated from small pieces (1 — 3 cm) of human saphenous vein and / or mammary artery.

Endothelial progenitor cells (EPCs) were isolated from these vascular tissues following standard collagenase digestion procedure.

Endothelial progenitor cells (EPCs) passage 10 and 15 were taken from low density cultures (A) Then induced to differentiate into mature endothelial cells (see methods).

Diabetes decreases the quantity and efficiency of EPCs (endothelial progenitor cells), whose function is to travel to injured areas and help with the formation of blood vessels and heal injuries quickly.

GH therapy has been shown to decrease fat mass, increase lean body mass, increase bone mineral density, reduce both LDL and total cholesterol, reduce carotid - artery intimal media thickness, increase the number and function of endothelial progenitor cells (which repair the vascular wall), increase exercise tolerance, and dramatically improve overall quality of life.8 9 10

As for the average American, no one is going to forego supersizing their hasty meal because of Neu5Gc, IGF - 1, endothelial progenitor cells, telomere length, mTOR or TMAO.

Endothelial progenitor cells and endothelial microparticles are independent predictors of endothelial function.