Sentences with word «endothelium»

Researchers from Massachusetts Eye and Ear have, for the first time, identified rapidly proliferating cells (known as «neural crest - derived progenitor cells») in the corneal endothelium of specimens from normal corneas and from corneas with Fuchs» Endothelial Corneal Dystrophy (FECD), a condition in which the cells responsible for keeping the cornea clear die prematurely — often leading to blindness.

Multiple hematoxylin - eosin - stained sections showed the presence of endothelium with intact Descemet membrane and no stromal tissue.

A study on postmenopausal women found that oral curcumin supplementation, in conjunction with an exercise regimen, helped to improve vascular endothelium function.

C: This panel, however, shows a complete lack of telomerase activity in peripheral endothelium as first seen in this study.

These studies, performed at Ohio University, are the first to identify the molecular mechanism of vitamin D3 - triggered restoration of the function of damaged endothelium in the cardiovasculature.

The Abstract: OBJECTIVE: The aim of this study was to investigate the effect of alpha - lipoic acid (ALA) treatment on endothelium - dependent and - independent vasodilatation, assessed by forearm blood flow (FBF), in patients with type 2 diabetes mellitus.

CONCLUSIONS: Intravenous ALA treatment improves endothelium - dependent vasodilatation in patients with type 2 diabetes, in the absence of effects on forearm vasomotor function.

Our body has no dietary need for saturated fat and an abundance of evidence supports the theory that saturated fat causes endothelium impairment leading to heart disease.

By contrast, ALA treatment increased endothelium - dependent vasodilatation to ACh (P < 0.05) but not to GTN compared with baseline.

Here we present a novel human Airway Lung - Chip containing a fully - differentiated human mucociliary airway epithelium separated from a pulmonary microvascular endothelium by a semi-permeable membrane that allows for immune cell infiltration.

BrdU fluorescent stainingin a niche of posterior limbal cells spreads to the human corneal endothelium following mechanical wounding.

In fact, the macromolecules in the CSF are actively transported by the capillary endothelium from brain to blood.

Under normal conditions, fluid from the center of the eye slowly leaks into the outer layers of cornea and is pumped back into the eye by a healthy endothelium.

His studies have shown that Schlemm's canal (SC) which is central in ocular fluid homeostasis, hence IOP, and thus is directly relevant to glaucoma, has a novel, specialized phenotype with properties that are a blend of blood and lymphatic endothelia based on expression of marker proteins of each lineage.

The team used cells lining brain capillaries called endothelium, and cells from placenta, which represent Zika's route across the blood - brain barrier and the transmission path from mother to child, respectively.

Such rejection is interferon - gamma - dependent and only occurs if the recipient endothelium expresses H - 2 (b).

These findings are in accord with the well - established roles of LFA1 and ICAM1 in supporting adhesion to and transmigration of lymphocytes across blood vessel endothelium into tissues (Rot and von Andrian, 2004).

Although stem cells have been demonstrated to reside in the peripheral and limbal region of the corneal epithelium [7 - 9], our experiments were not able to detect stem cells in the periphery of the corneal endothelium based on the absence of this marker.

Recent studies have provided evidence which suggests that there may be cell division in the peripheral endothelium [5].

Until now, no dengue viral proteins have been linked to vascular endothelium permeability (that is, vascular leakage).

While these studies were performed using a cellular model of hypertension, the implication of vitamin D3 on dysfunctional endothelium is much broader.

- SMA - positive cells (activated myofibroblasts) close to intact endothelium overlying a relatively acellular central myxoid

In this case, disruption of stable vascular endothelium disrupts this dormant niche and encourages the formation of a microenvironment that sparks micrometastatic outgrowth.»

It may be useful for corneal endothelium transplantation.

To obtain a viable donor of a Descemet membrane endothelium disc, we modified the Descemet membrane stripping technique and monitored the percentage of endothelial damage to the donor tissue preparation.

NG2 - positive cells ensheathed the isolectinB4 positive endothelium with pronounced coverage in arterioles, capillaries and venules (Supplementary Fig. 6b).

It also induces the secretion of vascular endothelium growth factor (VEGF), which leads to the increased growth of blood vessels and vascular permeability in inflammation (3).

Immune cells attaching to an inflamed endothelium, recreating the natural immune response that happens inside the lung.

Chairs: Jozef Dulak, Jagiellonian University and Shahin Rafii, Weill Cornell Medical College Karen K. Hirschi, Yale School of Medicine Role of vascular endothelial cells in stem cell generation and maintenance Ann Zovein, University of California, San Francisco Cell fate decisions in hemogenic endothelium (Stem Cells I under Cells and Vascular Beds)

This further promotes vasoconstriction and platelet aggregation (278) and decreases endothelium - dependent relaxation and NO production via impaired insulin signaling (277).

The primary epithelial cells are expanded as 3D organoids, dissociated, and cultured on a porous membrane within a microfluidic device with human intestinal microvascular endothelium cultured in a parallel microchannel under flow and cyclic deformation.