Sentences with phrase «endotoxin exposure»

However, endotoxin exposure did not stop mice lacking the A20 enzyme from becoming allergic to mites, showing that both the bacterial protein and the enzyme are needed to ensure the immune system did not overreact.

«Accordingly, we examined the effects of allergic disease on respiratory health in two sets of patients with COPD, one a nationally representative sample of 1,381 COPD patients from the National Health and Nutrition Survey III (NHANES III) and the other a cohort of 77 former smokers with COPD from a study of the effects of endotoxin exposure on health status.»

Not exact matches

This well - known theory proposed more than 2 decades ago postulates that early exposure to LPS (or endotoxin) decreases the risk of developing allergic disease (7 — 10).

But new experiments in mice suggest that one of our own enzymes, A20, is also essential for protecting against allergies, and those who lack this enzyme don't benefit from exposure to endotoxin.

GWI exposures alter the microbiome (i.e., bacterial content in the gut), and the affected microbiota then produce endotoxins, which pass through a thinned lining of the gut (i.e., leaky gut) and into the blood where they circulate throughout the body.

«[It] supports this idea that chronic inflammation in children, perhaps through exposure to bacterial endotoxin in the gut, is causing these different immune cell populations to be non-responsive to cytokine stimulation,» Petri said.